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Bilateral androblastoma (Sertoli-stromal cell tumor) of the ovary: a rare cause of virilization in a teenager

  • A. Warenik-Szymankiewicz1
  • R. SŁOPIEN´1,*,
  • M. Gaca2
  • H. Kędzia3
  • P. Kądziołka4
  • T. Opala4

1Department of Gynecological Endocrinology, University of Medical Sciences of Poznań, PL-60535 Poznan, Poland

2Department of Anesthesiology in Obstetrics and Gynecology University of Medical Sciences of Poznań, PL-60535 Poznan, Poland

3Department of Pathology University of Medical Sciences of PoznańPL-60535 Poznan, Poland

4Department of Mother’s and Child’s Health University of Medical Sciences of Poznań, Poland

DOI: 10.12892/ejgo201202217 Vol.33,Issue 2,March 2012 pp.217-218

Published: 10 March 2012

*Corresponding Author(s): R. SŁOPIEN´ E-mail: asrs@wp.pl

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Abstract

A case of a 17-year-old patient diagnosed with bilateral androblastoma of the ovary is presented. The patient was admitted because of secondary amenorrhea, hirsutism and acne. After clinical, ultrasonographic and hormonal examinations an androgen-producing ovarian tumor was suspected and consequently laparotomy with right ovarian tumor excision and left ovary exploration was carried out. During surgery the right ovarian tumor was excised and exploration of the left ovary revealed an ovarian tumor with a diameter of 10 mm, which was then also excised. The pathologic diagnosis was a bilateral androblastoma of the ovary measuring 40 mm x 30 mm x 20 mm in the right ovary and 10 mm in diameter in the left ovary. We concluded that androblastomas, in spite of their low incidence, are a possibility that should always be considered in women of all ages presenting with signs of virilization.

Keywords

Androblastoma; Virilization; Teenager

Cite and Share

A. Warenik-Szymankiewicz,R. SŁOPIEN´,M. Gaca,H. Kędzia,P. Kądziołka,T. Opala. Bilateral androblastoma (Sertoli-stromal cell tumor) of the ovary: a rare cause of virilization in a teenager. European Journal of Gynaecological Oncology. 2012. 33(2);217-218.

URL:

https://www.ejgo.net/articles/10.12892/ejgo201202217

References

[1] Scully R.E.: “Tumors of the Ovary and Maldeveloped Gonads”. Armed Forces Institute of Pathology 16, 2nd series, Washington DC 1979.

[2] Young R.H., Scully R.E.: “Ovarian Serotli-Leydig cell tumors. A clinicopathologic analysis of 207 cases”. Am. J. Surg. Pathol., 1985, 9, 543.

[3] Gerhenson D.M.: “Ovarian gern cell and stromal tumors”. In: Greer B.E., Berek J.S. (eds.): Gynecologic Oncology. Treatment Rationale and Techniques. New York, Elsevier, 1991, 167.

[4] Sanz O.A., Martinez P.R., Guarch R.T., Goni M.J.I., Alcazar J.L.Z.: “Bilateral Leydig cell tumour of the ovary: A rare cause of virilization in postmenopausal women”. Maturitas, 2007, 57, 214.

[5] Meldrum D.R., Abraham G.E.: “Peripheral and ovarian venous concentration of various steroid hormones in virilizing ovarian tumors”. Obstet. Gynecol., 1979, 53, 36.

[6] Munemura N., Nakamura T., Matsuura K., Maeyama M., Iwamasa T.: “Endocrine profile of an ovarian androblastoma”. Obstet. Gynecol., 1982, 15, 100S.

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