Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Article Menu
Export Article
More by Authors Links
Article Data
- Views 278
- Dowloads 124
Original Research
Open AccessEndometrioid ovarian cancer arising from an endometriotic cyst in a young patient
Endometrioid ovarian cancer arising from an endometriotic cyst in a young patient
- D. Zygouris1
- V. Leontara2
- G.M. Makris1
- C. Chrelias1
- E. Trakakis1
- Ch. Christodoulaki1
- P. PANAGOPOULOS1,*,
13rd Deptartment of Obstetrics & Gynaecology University of Athens, Greece
2Department of Pathology University of Athens, Greece
*Corresponding Author(s): P. PANAGOPOULOS E-mail: paninosrafaela@yahoo.gr
Abstract
Objective: To present a case of a young woman with ovarian endometrioid adenocarcinoma arising from an endometriotic cyst and review of the literature. Case Report: A 33-year-old woman, gravid 2, para 2 was admitted to our department with a 5 cm adnexal mass. Diagnostic laparoscopy was performed and pathological examination demonstrated an endometriotic cyst with an area of an ovarian endometrioid adenocarcinoma well differentiated, with no capsular invasion. One month after the operation the patient underwent MRI which revealed a 6 cm mass in the Douglas pouch. The multidisciplinary oncology council decided on exploratory laparotomy, which revealed no pathology. After that the multidisciplinary oncology council decided on adjuvant chemotherapy and the patient received four cycles of carboplatin/taxol. Conclusion: It should always be considered that even when there are no risk factors for malignancy occurrence, a high index of suspicion is necessary and will help to prevent delay in the diagnosis of this rare neoplasm.
Keywords
Endometriosis; Endometriosis-associated cancer; Ovarian endometrioid adenocarcinoma
Cite and Share
D. Zygouris,V. Leontara,G.M. Makris,C. Chrelias,E. Trakakis,Ch. Christodoulaki,P. PANAGOPOULOS. Endometrioid ovarian cancer arising from an endometriotic cyst in a young patient. European Journal of Gynaecological Oncology. 2012. 33(3);324-325.
References
[1] Giudice L.C., Kao L.C.: “Endometriosis”. Lancet, 2004, 364, 1789.
[2] Cramer D.W., Missmer S.A.: “The epidemiology of endometriosis”. Ann. N.Y. Acad. Sci, 2002, 955, 11.
[3] Sampson J.A.: “Metastatic or embolic endometriosis, due to the menstrual dissemination of endometrial tissue into the venous circulation”. Am. J. Pathol., 1927, 3, 93.
[4] Scott R.B.: “Malignant changes in endometriosis”. Obstet. Gynecol., 1953, 2, 283.
[5] Heaps J.M., Nieberg R.K., Berek J.S.: “Malignant neoplasms arising in endometriosis”. Obstet. Gynecol., 1990, 75, 1023.
[6] Ness R.B.: “Endometriosis and ovarian cancer: thoughts on shared pathophysiology”. Am. J. Obstet. Gynecol., 2003, 189, 280.
[7] Stern R.C., Dash R., Bentley R.C., Snyder M.J., Haney A.F., Robboy S.J.: “Malignancy in endometriosis: frequency and comparison of ovarian and extraovarian types”. Int. J. Gynecol. Pathol., 2001, 20, 133.
[8] Melin A., Sparén P., Persson I., Bergqvist A.: “Endometriosis and the risk of cancer with special emphasis on ovarian cancer”. Hum. Reprod., 2006, 21, 1237.
[9] Weiss N.S.: “Measuring the separate effects of low parity and its antecedents on the incidence of ovarian cancer”. Am. J. Epidemiol., 1988, 128, 451.
[10] Kobayashi H., Sumimoto K., Moniwa N., Imai M., Takakura K., Kuromaki T. et al.: “Risk of developing ovarian cancer among women with ovarian endometrioma: a cohort study in Shizuoka, Japan”. Int. J. Gynecol. Cancer, 2007, 17, 37.
[11] Dinulescu D.M., Ince T.A., Quade B.J., Shafer S.A., Crowley D., Jacks T.: “Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer”. Nat. Med., 2005, 11, 63.
Abstracted / indexed in
Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.
Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.
Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.
JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.
Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.
BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.
Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.
Submission Turnaround Time
Conferences
Top