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Case Reports

Open Access

Spindle-cell epithelioma of the vagina diagnosed during pregnancy - a case report

  • S. Pantovic1
  • A. Stefanovic1,2
  • J. Stojnic1,2,*,
  • K. Jeremic1,2
  • R. Sparic1
  • S. Kadija1,2
  • S. Milenkovic3

1Clinic for Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia

2School of Medicine, University of Belgrade, Belgrade, Serbia

3Department for Pathology, Clinical Center of Serbia, Belgrade, Serbia

DOI: 10.12892/ejgo2614.2015 Vol.36,Issue 2,April 2015 pp.219-222

Published: 10 April 2015

*Corresponding Author(s): J. Stojnic E-mail: jelence_01@open.telekom.rs

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Abstract

Spindle-cell epithelioma or ”mixed tumor” of the vagina is an unusual and intriguing vaginal tumor consisting of both epithelial and mesenchymal components. A case of spindle-cell epithelioma of the vagina diagnosed at delivery of a 31-year-old primiparous woman is described. The excision of the mass was performed immediately after the delivery, which was uneventful. The patient was regularly followed up and no evidence of local recurrence or dissemination was found 40 months after surgery. The presentation and the diagnosis of this kind of tumor in pregnancy, and its effect on the pregnancy and delivery are still largely unknown. Since it is unlikely that any institution will have a large number of patients with this rare disease, case reports add further information to this entity. As the number of cases studied is small, close follow-up is recommended although there has been no report in the literature of metastasis so far.

Keywords

Spindle-cell epithelioma; Mixed tumor; Vagina; Pregnancy.

Cite and Share

S. Pantovic,A. Stefanovic,J. Stojnic,K. Jeremic,R. Sparic,S. Kadija,S. Milenkovic. Spindle-cell epithelioma of the vagina diagnosed during pregnancy - a case report. European Journal of Gynaecological Oncology. 2015. 36(2);219-222.

URL:

https://www.ejgo.net/articles/10.12892/ejgo2614.2015

References

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[2] Laspas F., Roussakis A., Papadopoulos S., Fanariotis I., Kritikos N., Kehagias D.: “Mixed tumor of the vagina: sonographic and magnetic resonance imaging findings”. Ultrasound Obstet. Gynecol., 2010, 35, 617.

[3] Branton P.A., Tavassoli F.A.: “Spindle cell epithelioma, the so-called mixed tumor of the vagina. A clinicopathologic, immunohistochemical, and ultrastructural analysis of 28 cases”. Am. J. Surg. Pathol., 1993, 17, 509.

[4] Wright R.G., Buntine D.W., Forbes K.L.: “Recurrent benign mixed tumor of the vagina”. Gynecol. Oncol., 1991, 40, 84.

[5] Skelton H., Smith K.J.: “Spindle cell epithelioma of the vagina shows immunohistochemical staining supporting its origin from a primitive/progenitor cell population”. Arch. Pathol. Lab. Med., 2001, 125, 547.

[6] Oliva E., Gonzales L., Dionigi A., Young R.H.: “Mixed tumors of the vagina: an immunohistochemical study of 13 cases with emphasis on the cell of origin and potential aid in differential diagnosis”. Mod. Pathol., 2004, 17, 1243.

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