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Small cell carcinoma of the ovary of the hypercalcemic type (SCCOHT) – case report
1 Gynecology Department, Poznań University of Medical Sciences, Poznań, Poland
2Perinatology and Gynecology Department, Poznań University of Medical Sciences, Poznań, Poland
*Corresponding Author(s): J. Lubin E-mail: jola.lubin@gmail.com
Small cell carcinoma of the ovary of the hypercalcemic type (SCCOHT) is a very rare malignant disease, seen mostly in young women, with a very poor prognosis. There is no standard treatment for patients with this disease and most literature is limited to short series or case reports. This report describes the case of a 34-year-old woman with aggressive course of SCCOHT and poor outcome. What proved difficult was the process of establishing the diagnosis due to non-specific first symptoms of disease and consequently the combined treatment of surgery and chemotherapy with concurrent side effects.
Ovarian cancer; Small cell carcinoma of hypercalcemic type.
J. Lubin,M. Pawałowska,A. Markowska,A. Bielas. Small cell carcinoma of the ovary of the hypercalcemic type (SCCOHT) – case report. European Journal of Gynaecological Oncology. 2015. 36(1);88-90.
[1] Estel R., Hackethal A., Kalder M., Münstedt K.: “Small cell carcinoma of the ovary of the hypercalcaemic type: an analysis of clinical and prognostic aspects of a rare disease on the basis of cases published in the literature”. Arch. Gynecol. Obstet., 2011, 284, 1277.
[2] Harrison M.L., Hoskins P., du Bois A., Quinn M., Rustin G.J., Ledermann J.A., et al.: “Small cell of the ovary, hypercalcemic type - analysis of combined experience and recommendation for management. A GCIG study”. Gynecol. Oncol., 2006, 100, 233.
[3] Distelmaier F., Calaminus G., Harms D., Sträter R., Kordes U., Fleischhack G., et al.: “Ovarian small cell carcinoma of the hypercalcemic type in children and adolescents: a prognostically unfavorable but curable disease”. Cancer, 2006, 107, 2298.
[4] Young R.H., Oliva E., Scully R.E: “Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathological analysis of 150 cases”. Am. J. Surg. Pathol., 1994, 18, 1102.
[5] Oliva E.: “Small cell carcinoma of ovary, hypercalcemic type: an update on an enigmatic neoplasm”. Pathol. Case Rev., 2006, 11, 43.
[6] Taraszewski R., Rosman P.M., Knight C.A., Cloney D.J.: “Small cell carcinoma of the ovary”. Gynecol. Oncol., 1991, 41, 149.
[7] Baeyens L., Amat S., Vanden Houte K., Vanhoutte P., L’Hermite M.: “Small cell carcinoma of the ovary successfully treated with radiotherapy only after surgery: case report”. Eur. J. Gynaec. Oncol., 2008, 29, 535.
[8] Dickersin G.R., Kline I.W., Scully R.E.: “Small cell carcinoma of the ovary with hypercalcemia: a report of eleven cases”. Cancer, 1982, 49, 188.
[9] Pautier P., Ribrag V., Duvillard P., Rey A., Elghissassi I., Sillet-Bach I., et al.: “Results of a prospective dose-intensive regimen in 27 patients with small cell carcinoma of the ovary of the hypercalcemic type”. Ann. Oncol., 2007; 18: 1985.
[10] Senekjian E.K., Weiser P.A., Talerman A., Herbst A.L.: “Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin and etoposide in the treatment of small cell carcinoma of the ovary”. Cancer, 1989, 64, 1183.
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