Article Data

  • Views 2057
  • Dowloads 103

Original Research

Open Access

The differences of phyllodes and acoustic attenuation in breast lesions diagnosed with Breast Imaging-Reporting and Data System for Ultrasonography (BI-RADS-US) category 4C

  • Y.Y. Li1
  • C. Liu1
  • J. Geng1
  • J.G. Li2
  • F. Jin2
  • X.M. Wang1

1Department of Ultrasound Diagnosis, the First Affiliated Hospital of China Medical University, Shenyang, China

2Department of Breast Surgery, the First Affiliated Hospital of China Medical University, Shenyang, China

DOI: 10.12892/ejgo2635.2015 Vol.36,Issue 3,June 2015 pp.249-297

Published: 10 June 2015

*Corresponding Author(s): X.M. Wang E-mail: cnjinfeng@126.com

Abstract

Objective: This study aimed to discuss the differences of malignant findings in breast lesions diagnosed with Breast Imaging-Reporting and Data System for Ultrasonography (BI-RADS-US) category 4C to determine which malignant findings are more important. Materials and Methods: A total of 159 cases of breast lesions diagnosed with BI-RADS-US category 4C were analyzedretrospectively. All patients got pathological results (81 cases of benign; 78 cases of breast cancer). Two doctors scanned and diagnosed the patients, with another doctor recording ultrasonographic findings retrospectively. The differences were compared by means of the Chi-square (χ2) test. Results: Phyllodes and acoustic attenuation had statistical differences in the comparison of breast lesions (p < 0.05). Irregular shape, indistinct boundary, poorly-defined margin, penetrating or tortuous surrounding vessels, RI ≥ 0.7, and microcalcification had no statistical differences in the comparison of benign and malignant breast lesions. Conclusions: Phyllodes and acoustic attenuation are the more important malignant ultrasonographic findings of breast cancer. The malignant ultrasonographic findings are not unique for breast cancer.

Keywords

Malignant ultrasonographic findings of breast; BI-RADS-US; Differential diagnosis of breast lesions.

Cite and Share

Y.Y. Li,C. Liu,J. Geng,J.G. Li,F. Jin,X.M. Wang. The differences of phyllodes and acoustic attenuation in breast lesions diagnosed with Breast Imaging-Reporting and Data System for Ultrasonography (BI-RADS-US) category 4C. European Journal of Gynaecological Oncology. 2015. 36(3);249-297.

References

[1] Olopade O.I., Grushko T.A., Nanda R., Huo D.: “Advances in breast cancer: pathways to personalized medicine”. Clin. Cancer Res., 2008, 14, 7988.

[2] Burnside E.S., Sickles E.A., Bassett L.W., Rubin D.L., Lee C.H., Ikeda D.M., et al.: “The ACR BI-RADS experience: learning from history”. J. Am. Coll. Radiol., 2009, 6, 851.

[3] Ojeda-Fournier H., Nguyen J.Q.: “How to improve your breast cancer program: standardized reporting using the new American College of Radiology Breast Imaging-Reporting and Data System”. Indian J. Radiol. Imaging, 2009, 19, 266.

[4] Kelly K.M., Dean J., Lee S.J., Comulada W.S.: “Breast cancer detection: radiologists’ performance using mammography with and without automated whole-breast ultrasound”. Eur. Radiol., 2010, 20, 2557.

[5] Moon H.J., Kim M.J., Kwak J.Y., Yoon J.H., Kim S.J., Sohn Y.M., et al.: “Malignant lesions initially categorized as probably benign breast lesions: retrospective review of ultrasonographic, clinical and pathologic characteristics”. Ultrasound Med. Biol., 2010, 36, 551.

[6] Moon H.J., Kim M.J., Kwak J.Y., Kim E.K.: “Prob-ably benign breast lesions on ultrasonography: a retrospective review of ultrasonographic features and clinical factors affecting the BI-RADS categorization”. Acta Radiol., 2010, 51, 375.

[7] Zahl P.H., Mæhlen J.: “Overdiagnosis of breast cancer after 14 years of mammography screening”. Tidsskr. Nor. Laegeforen., 2012, 132, 414.

[8] Raza S., Chikarmane S.A., Neilsen S.S., Zorn L.M., Birdwell R.L.: “BI-RADS 3, 4, and 5 lesions: value of US in management—followup and outcome”. Radiology, 2008, 248, 773.

[9] Choi B.B., Kim S.H., Shu K.S.: “Lobular lesions of the breast: imaging findings of lobular neoplasia and invasivelobular carcinoma”. J. Reprod. Med., 2012, 57, 26.

[10] Tan H., Zhang S., Liu H., Peng W., Li R., Gu Y., et al.: “Imaging findings in phyllodes tumors of the breast”. Eur. J. Radiol., 2012, 81, e62.

[11] Gurleyik G., Aktekin A., Aker F., Karagulle H., Saglamc A.: “Medical and surgical treatment of idiopathic granulomatous lobular mastitis: a benign inflammatory disease mimicking invasive carcinoma”. J. Breast Cancer, 2012, 15, 119.

[12] Adamietz B.R., Kahmann L., Fasching P.A., Schulz-Wendtland R., Uder M., Beckmann M.W., et al.: “Differentiation between phyllodes tumor and fibroadenoma using real-time elastography”. Ultraschall Med., 2011, 32, E75.

[13] Gatta G., Iaselli F., Parlato V., Di Grezia G., Grassi R., Rotondo A.: “Differential diagnosis between fibroadenoma, giant fibroadenoma and phyllodes tumour: sonographic features and core needle biopsy”. Radiol. Med., 2011, 116, 905.

[14] Tamaki K., Sasano H., Ishida T., Ishida K., Miyashita M., Takeda M., et al.: The correlation between ultrasonographic findings and pathologic features in breast disorders”. Jpn. J. Clin. Oncol., 2010, 40, 905.

[15] Kim S.H., Cha E.S., Park C.S., Kang B.J., Whang I.Y., Lee A.W., et al.: “Imaging features of invasive lobular carcinoma: comparison with invasive ductal carcinoma”. Jpn. J. Radiol., 2011, 29, 475.

[16] Doyle T.E., Factor R.E., Ellefson C.L., Sorensen K.M., Ambrose B.J., Goodrich J.B., et al.: “High-frequency ultrasound for intraoperative margin assessments in breast conservation surgery: a feasibility study”. BMC Cancer, 2011, 11, 444.

[17] Kanaev C.V., Novikov S.N., Semiglazov V.F., Krivorot’ko P.V., Zhukova L.A., Krzhivitskiĭ P.I.: “Early diagnosis of breast cancer with scintimammography and ultrasound”. Vopr. Onkol., 2011, 57, 622.

[18] Wang X., Xu P., Wang Y., Grant E.G.: “Contrast-enhanced ultrasonographic findings of different histopathologic types of breast cancer”. Acta Radiol., 2011, 52, 248.

[19] Memis A., Ozdemir N., Parildar M., Ustun E.E., Erhan Y.: “Mucinous (colloid) breast cancer: mammographic and US features with histologic correlation”. Eur. J. Radiol., 2000, 35, 39.

[20] Bode M.K., Rissanen T.: “Imaging findings and accuracy of core needle biopsy in mucinous carcinoma of the breast”. Acta Radiol., 2011, 52, 128.

[21] Bode M.K., Rissanen T., Apaja-Sarkkinen M.: “Ultrasonography and core needle biopsy in the differential diagnosis of fibroadenoma and tumor phyllodes”. Acta Radiol., 2007, 4, 708.

Submission Turnaround Time

Top