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Case Reports

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Squamous cell carcinoma of Bartholin gland coexistent with human papillomavirus

  • Z. Topolovec1
  • V. Blažičević2
  • S. Šijanović1
  • D. Vidosavljević3,*,

1Department of Obstetrics and Gynecology, Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia

2Institute for Pathology and Forensic Medicine, KBC Osijek, Osijek, Croatia

3Department of Gynecology and Obstetrics, Vukovar General Hospital, Vukovar, Croatia

DOI: 10.12892/ejgo2654.2015 Vol.36,Issue 4,August 2015 pp.482-484

Published: 10 August 2015

*Corresponding Author(s): D. Vidosavljević E-mail: domagoj.vidosavljevic@gmail.com

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Abstract

Squamous cell carcinoma of the Bartholin’s glands is a very rare form of vulvar neoplasm. This case presents a 46-year-old female diagnosed with advanced primary squamous cell cancer of the Bartholin glands that has proven positive for human papillomavirus (HPV). The patient was treated with a wide excision of the tumor, an ipsilateral lymphadenectomy, and an adjuvant chemotherapy and irradiation. After two years of follow-up the patient remains in remission.

Keywords

Squamous cell cancer; Bartholin’s gland; Human papillomavirus.

Cite and Share

Z. Topolovec, V. Blažičević, S. Šijanović, D. Vidosavljević. Squamous cell carcinoma of Bartholin gland coexistent with human papillomavirus. European Journal of Gynaecological Oncology. 2015; 36(4): 482-484. doi: 10.12892/ejgo2654.2015

URL:

https://www.ejgo.net/articles/10.12892/ejgo2654.2015

References

[1] Hill D.S., Butterfield A.: “Bartholin’s gland squamous cell carcinoma, a rare vulvar neoplasm”. Journal of Diagnostic Medical Sonography, 2010, 26, 296.

[2] Hillemanns P., Wang X.: “Integration of HPV-16 and HPV-18 DNA in vulvar intraepithelial neoplasia”. Gynecol. Oncol., 2006, 100, 276.

[3] Van de Nieuwenhof H.P., van Kempen L.C., de Hullu J.A., Bekkers R.L., Bulten J., Melchers W.J., Massuger L.F.: “The etiologic role of HPV in vulvar squamous cell carcinoma fine tuned”. Cancer Epidemiol. Biomarkers Prev., 2009, 18, 2061.

[4] Wilkinson E.J.: “Premalignant and malignant tumors of the vulva”. In: Kurman R.J., (ed). Blaustein’s pathology of the female genital tract, 5th ed., New York: Springer-Verlag, 2002, 99.

[5] Clement B.P., Young R.H.: “Malignant tumors of the vulva”. In: Clement B.P., Young R.H. (eds). Atlas of gynecologic surgical pathology, 3rd ed., Philadelphia: Saunders Elsevier, 2014, 29.

[6] Pinn M.E., Austin L.M., Schomas D.A., Miller R.C.: “Case report from Mayo Clinic: Locally advanced Bartholin gland carcinoma”. Radiol. Oncol., 2007, 41, 72.

[7] Chamallian D.I., Taylor H.B.: “Primary carcinoma of Bartholin’s gland. A report of 24 patients”. Obstet. Gynecol., 1972, 39, 489.

[8] Dodson M.G., O’Leary J.A., Averette H.E.: “Primary carcinoma of Bartholin gland”. Obstet. Gynecol., 1970, 37, 578.

[9] Felix J.C., Cote R.J., Kramer E.E., Saigo P., Goldman G.H.: “Carcinomas of Bartholin’s gland. Histogenesis and the etiological role of human papillomavirus”. Am. J. Pathol., 1993, 142, 925.

[10] Gissman L.: “Papillomaviruses and their association with cancer in animals and in man”. Cancer Surv., 1984, 3, 161.

[11] Schmidt D., Bergeron C., Denton K.J., Ridder R., European CINtec Cytology Study Group: “p16/ki-67 dual-stain cytology in the triage of ASCUS and LSIL papanicolaou cytology: results from the European equivocal or mildly abnormal Papanicolaou cytology study”. Cancer Cytopathol., 2011, 119, 158.

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