Article Data

  • Views 2014
  • Dowloads 130

Case Reports

Open Access

Skin metastases of vulvar squamous cell carcinoma. Presentation of a rare case

  • C. Sofoudis1,*,
  • N. Salakos1
  • M. Tolia2
  • E. Carvounis3
  • A. Melloy3
  • I. Kouvaris2
  • G. Fragoulidis4

12nd Department of Obstetrics and Gynecology, Aretaieion University Hospital, Medical School of Athens, Athens, Greece

21st Department of Radiology, Radiation Oncology Unit, Aretaieion University Hospital, Medical School of Athens, Athens, Greece

3Department of Pathology, Aretaieion University Hospital, Medical School of Athens, Athens, Greece

42nd Department of Surgery, Aretaieion University Hospital, Medical School of Athens, Athens, Greece

DOI: 10.12892/ejgo2797.2015 Vol.37,Issue 1,February 2016 pp.126-128

Published: 10 February 2016

*Corresponding Author(s): C. Sofoudis E-mail: chrisostomos.sofoudis@gmail.com

PDF (129.38 kB) View Full-text

Abstract

Skin metastases secondary to vulvar carcinoma is an infrequent clinical entity. The authors describe a case of squamous vulvar carcinoma, which presented with cutaneous involvement as a part of distant spread. After a radical vulvectomy, bilateral inguino-femoral lymphadenectomy, and adjuvant radiotherapy, the patient developed multiple cutaneous metastases in lower extremities. This case was unique in presentation, with skin metastases secondary from vulvar carcinoma, and indicated advance disease and poor prognosis.


Keywords

Vulvar cancer; Skin metastases; Surgery; Radiotherapy.

Cite and Share

C. Sofoudis, N. Salakos, M. Tolia, E. Carvounis, A. Melloy, I. Kouvaris, G. Fragoulidis. Skin metastases of vulvar squamous cell carcinoma. Presentation of a rare case. European Journal of Gynaecological Oncology. 2016; 37(1): 126-128. doi: 10.12892/ejgo2797.2015

References

[1] Rogers L.J., Howard B., Van Wijk L., Wei W., Dehacck K., Soeters R., Denny L.A.: “Chemoradiation in advanced vulval carcinoma”. Int J Gynecol Cancer, 2009, 19, 745.

[2] Tobias D.H., Smith H.O., Jones J.G., Anderson P., Runowicz C.D., Goldgerg G.L.: “Cutaneus metastases from squamous cell carcinoma of the vulva”. Eur. J. Gynaecol. Oncol., 1995, 16, 382.

[3] Brownstein M.H., Helwig E.B.: “Patterns of cutaneus metastasis”. Arch. Dermatol., 1972, 105, 862.

[4] Fernandez-Flores A., Pol A., Juanes F., Crespo L.G.: “Immunohis-tochemical phenotype of cutaneous cribriform carcinoma with a panel of 15 antibodies”. Med. Mol. Morphol., 2007, 40, 212.

[5] Kouloulias V., Triantopoulou S., Efstathopoulos E., Platoni K., Kouvaris J., Uzunoglou N., et al.: “Microwave hyperthermia in conjuction with radiotherapy in superficial tumors: correlation of thermal parameters with tumour progression”. West Indian Med. J., 2013, 62, 752.

[6] Russell A.H., Van der Zee A.G.J.: “Vulvar and vaginal carcinoma”. In: Gunderson L.L., Tepper J.E. (eds). Clinical Radiation Oncology, 3rd ed. Philadelphia, PA: Elsevier Saunders, 2012, 1241.

[7] Tolia M., Tsoukalas N., Platoni K., Dilvoi M., Pantelakos P., Kelekis N., et al.: “Metastatic bone involvement in vulvar cancer: report of a rare case and review of the literature”. Eur. J. Gynaecol. Oncol., 2012, 33, 411.

[8] Leys C.M., Hartenbach E.M., Hafez G.R., Mahvi D.M.: “Screening for occult nodal metastasis in squamous cell carcinoma of the vulva”. Int. J. Gynecol. Pathol., 2000, 19, 243.

[9] Oonk M.H., van Hemel B.M., Hollema H., de Hullu J.A., Ansink A.C., Vergote I., et al.: “Size of sentinelnode involvement and surgical in early stage vulvar cancer:results from GROINSS-V, a multicentre observational study”. Lancet Oncol., 2010, 11, 646.

[10] Levenback C.F., Ali S., Coleman R.L., Gold M.A., Fowler J.M., Judson P.L., et al.: “Lymphatic mapping and sentinel lymph node biopsy in women with squamous cell carcinoma”. Gynecol. Oncol., 1990, 37, 9.

[11] Makar A.P.H., Scheistroen M., Van Den Weyngaert D., Trope C.G.: “Surgical management of stage I and II vulvar cancer: the role of the sentinel node biopsy. Review of the literature”. Int. J. Gynecol. Cancer, 2001, 11, 255.

[12] Hansen N.M., Grube B.J., Giulano A.E.: “The time has come to change the algorithm for the surgical management of early breast cancer”. Arch. Surg., 2002, 137, 1131.

[13] Terada K.Y., Shimizu D.M., Wong J.H.: “Sentinel node dissection and ultrastaging in squamous cell carcer of the vulva”. Gynecol. Oncol., 2000, 76, 40.

[14] Ceydeli A., Rucinski J., Klipfel A.: “Vulvar suamous cell carcinoma metastaticto skin of the forearm”. Dermatol. Surg., 2003, 29, 662.

[15] Triantopoulou S., Efstathopoulos E., Platoni K., Uzunoglou N., Kelekis N., Kouloulias V.: “Radiotherapy in conjunction with superficial and intracavitary hyperthermia for the treatment of solid tumors: survival and thermal parameters”. Clin. Transl. Oncol., 2013, 15, 95.

Submission Turnaround Time

Top