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Original Research

Open Access

Accuracy of intra-operative frozen section and its role in the diagnostic evaluation of ovarian tumors

  • A. Abudukadeer1,*,
  • S. Azam1
  • B. Zunong2
  • A. Zuoremu Mutailipu1
  • B. Huijun1
  • L. Qun1

1Department of Gynaecology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China

2The encoding room of medical record department, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China

DOI: 10.12892/ejgo2818.2016 Vol.37,Issue 2,April 2016 pp.216-220

Published: 10 April 2016

*Corresponding Author(s): A. Abudukadeer E-mail: abida0724@126.com

Abstract

Objective: This retrospective study was undertaken to evaluate the accuracy and role of intra-operative frozen section in the diagnosis of ovarian tumors. Materials and Methods: Retrospective study of 804 ovarian frozen section results between June 2010 and June 2014 was examined to determine the accuracy of frozen section diagnosis. The intra-operative frozen section diagnosis was compared with the permanent (paraffin) section and the overall accuracy, sensitivity, specificity, and positive and negative predictive values of the frozen section were studied. Results: The overall accuracy to determine the status of malignancy was 92.6%. There were 38 (7.4%) false negative and no false positive frozen section diagnoses.The sensitivity, specificity, and positive predictive and negative predictive values for benign ovarian tumors were 100.0%, 97.0%, 91.3%, and 100.0%, respectively; for borderline tumors they were 64.3%, 97.0%, 91.5%, and 94.0%, respectively, and for malignant tumors they were 90.0%, 100.0%, 100.0%, and 85.5%, respectively. Conclusion: This study concluded that frozen section appears to be an adequate technique for the histopathological diagnosis of ovarian tumors, with some limitations observed among borderline and mucinous tumors.

Keywords

Intra-operative frozen section; Permanent (paraffin) section; Ovarian tumors.

Cite and Share

A. Abudukadeer,S. Azam,B. Zunong,A. Zuoremu Mutailipu,B. Huijun,L. Qun. Accuracy of intra-operative frozen section and its role in the diagnostic evaluation of ovarian tumors. European Journal of Gynaecological Oncology. 2016. 37(2);216-220.

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