Solitary fibrous tumor arising in the mons pubis: a case report

Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms of fibroblastic origin that mainly arise from the pleura. Although SFTs arising at numerous extrapleural locations have been reported, extrapleural soft tissue SFTs are extremely rare. The diagnosis of SFTs is based on histologic findings. However, given the histological variability of SFTs, immunohistochemical examination becomes important in their diagnosis. Complete surgical resection is the only and a very important prognostic factor and is recommended for the treatment of both benign and malignant SFTs with a curative intent. Here, the author reports what he believes to be the first case of an SFT originating in the mons pubis.

Solitary fibrous tumors; Extrapleural; Mons pubis.

[1] Gold J.S., Antonescu C.R., Hajdu C., Ferrone C.R., Hussain M., Lewis J.J., et al.: “Clinicopathologic correlates of solitary fibrous tumors”. Cancer, 2002, 94, 1057.

[2] Vallat-Decouvelaere A.V., Dry S.M., Fletcher C.D.: “Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intra-thoracic tumors”. Am. J. Surg. Pathol., 1998, 22, 1501.

[3] Taki M., Baba T., Mandai M., Suzuki A., Mikami Y., Matsumura N., et al.: “Solitary fibrous tumor arising slowly in the vulva over 10 years: case report and review”. J. Obstet. Gynaecol. Res., 2012, 38, 884.

[4] Robinson L.A.: “Solitary fibrous tumor of the pleura”. Cancer Control, 2006, 13, 264.

[5] Penel N., Amela E.Y., Decanter G., Robin Y.M., Marec-Berard P.: “Solitary fibrous tumors and so-called hemangiopericytoma”. Sarcoma, 2012, 2012, 690251.

[6] Shanbhogue A.K., Prasad S.R., Takahashi N., Vikram R., Zaheer A., Sandrasegaran K.: “Somatic and visceral solitary fibrous tumors in the abdomen and pelvis: cross-sectional imaging spectrum”. Radiographics, 2011, 31, 393.

[7] Sawada N., Ishiwata T., Naito Z., Maeda S., Sugisaki Y., Asano G.: “Immunohistochemical localization of endothelial cell markers in solitary fibrous tumor”. Pathol Int., 2002, 52, 769.

[8] Hanau C.A., Miettinen M.: “Solitary fibrous tumor: histological and immunohistochemical spectrum of benign and malignant variants presenting at different sites”. Hum. Pathol., 1995, 26, 440.

[9] Kawamura S., Nakamura T., Oya T., Ishizawa S., Sakai Y., Tanaka T., Saito S., Fukuoka J.: “Advanced malignant solitary fibrous tumor in pelvis responding to radiation therapy”. Pathol. Int., 2007, 57, 213.

[10] England D.M., Hochholzer L., McCarthy M.J.: “Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases”. Am. J. Surg. Pathol., 1989, 13, 640.