Article Data

  • Views 448
  • Dowloads 121

Case Reports

Open Access

Port-site metastasis after laparoscopic surgery for mature cystic teratoma

  • Tomoko Sho1,*,
  • Rie Urabe1
  • Toru Hachisuga1

1Department of Obstetrics and Gynecology, University of Occupationl and Environmental Health, Japan, Yahatanishi-ku, Kitakyushu, Japan

DOI: 10.12892/ejgo2846.2016 Vol.37,Issue 2,April 2016 pp.247-250

Published: 10 April 2016

*Corresponding Author(s): Tomoko Sho E-mail:


In this case, a 27-year-old nulliparous woman with a pelvic multiple cystic mass was treated and found with ovarian mature cystic teratoma associated with port-site metastasis (PSM). Suspecting recurrence of mature cystic teratoma, a second laparoscopic surgery found a small mass, on the right under abdomen's peritoneal membrane, at the laparoscopic port sites of the initial operation. Pathological report of the peritoneal mass and left ovarian tumor confirmed a mature cystic teratoma. To the best of the authors' knowledge, this is the first reported PSM in associated with benign ovarian tumor.


Mature cystic teratoma; Port-site metastasis.

Cite and Share

Tomoko Sho,Rie Urabe,Toru Hachisuga. Port-site metastasis after laparoscopic surgery for mature cystic teratoma . European Journal of Gynaecological Oncology. 2016. 37(2);247-250.


[1] Dobronte Z., Wittmann T., Karacsony G.: “Rapid development of malignant metastases in the abdominal wall after laparoscopy”. Endoscopy, 1978, 10, 127.

[2] Patsner B., Damien M.: “Umbilical metastases from a stage IB cervical cancer after open laparoscopy: a case report”. Fertil. Steril., 1992, 58, 1248.

[3] Zivanovic O., Sonoda Y., Diaz J.P., Levine D.A., Brown C.L., Chi D. S., et al.: “The rate of port-site metastasis after 2251 laparoscopic procedures in women with underlying malignant disease”. Gynecol. Oncol., 2008, 111, 431.

[4] Bacha E.A., Barber W., Ratchford W.: “Port site metastases of adenocarcinoma of the fallopian tube after laparoscopically assisted vaginal hysterectomy and salpingo-oophorectomy”. Surg. Endosc., 1996, 10, 1102.

[5] Martinez A., Querleu D., Leblanc E., Narducci F., Ferron G., et al.: “Low incidence of port-site metastases after laparoscopic stagein of uterine cancer”. Gynecol. Oncol., 2012, 118, 145.

[6] Morice P., Viala J., Pautier P., Lhommé C., Duvillard P., Castaigne D., et al.: “Port-site metastasis after laparoscopic surgery for gynecologic cancer. A report of six cases”. J. Reprod. Med., 2000, 45, 837.

[7] Couteau C., Lazard A., Marcelli M., Estrade JP., Aqostini A., Cravello L., et al.: “Port-site metastasis after retroperitoneal lymphadenectomy for endometirial adenocarcinoma.” Gynecol. Obstet., Fertil., 2012, 42, 129.

[8] Sheoherd J.H., Carter P.G. Lowe D.G.: “Wound recurrence by implantation of a borderline ovarian tumor following laparoscopic removal”. Br. J. Obstet. Gynaecol., 1994, 101, 265.

[9] Shoup M., Brennan MF., Karpen MS., Gillern SM., McMahan RL., Conlon KC., et al.: “Port-site metastasis after diagnostic laparoscopy for upper gastorointestinal tract malignancies: an uncommon entity”. Ann. Surg. Oncol., 2002, 9, 632.

[10] Ramirez P.T., Wolf J.K., Levenback C.: “Laparoscopic port-site metastasis: etiology and prevention”. Gynecol. Oncol., 2003, 91, 179.

[11] Smidt V.J., Singh D.M., Hurteau J.A., Hurd W.W.: “Effect of carbon dioxide on human ovarian carcinoma cell prowth”. Am. J. Obstet. Gynecol., 2001, 185, 1314.

[12] Targarona E.M., Martinez J., Nadal A., Balaque C., Cardesa A., Pascual S., et al.: “Cancer dissemination during laparoscopic surgery: tubes, gas, and cells”. World J. Surg., 1998, 22, 55.

[13] Moreria H. Jr., Yamagushi T., Wexner S., Singer L., Zhao R., Baiq M. K., et al.: “Effect of pneumoperitoneal pressure on tumor dissemination and tumor recurrence at port-site and midline incisions”. Am. Surg., 2001, 67, 369.

[14] Neuhaus S.J., Watson D.I., Ellis T., Rowland R., Rofe A.M., Pike G. K., et al.: “Wound metastasis after laparoscopy with different insufflation gases”. Surgery, 1998, 123, 579.

[15] Yamagushi K., Hirabayashi Y., Shiromizu A., Shiraishi N., Adachi Y., Kitano S.: “Enhancement of port site metastasis by hyaluronic acid under CO2 pneumoperitoneum in a murine model”. Surg. Endosc., 2001, 15, 504.

[16] Hirabayashi Y., Yamaguchi K., Shiraishi N., Adachi Y., Saiki I., Kitano S.: “Port-site metastasis after CosPeumoperitoneum; role of adhesion molecules and prevention with antiadhesion molecules”. Surg. Endosc., 2004, 18, 1113.

[17] Jacobi C.A., Ordemann J., Bohm B., Zieren HU., Sabat R., Muller J. M., et al.: “Inhibition of peritoneal tumor cell growth and implan-tation in laparoscopic surgery in a rat model”. Am. J. Surg., 1997, 174, 359.

[18] Ushakov F.B., Meirow D., Prus D., Libson E., Benshushan A., Ro-ansky N.: “Parastic ovarian dermoid tumor of the omentum – a review of the literature and report of two new cases”. Eur. J. Obstet. Gynecol. Reprod. Biol., 1998., 81, 77.

[19] Truong L.D., Jurco S. 3rd., McGavran M.H.: “Gliiomatosis peritonei: report of two cases and review of literature”. Am. J. Surg. Pathol., 1982, 6, 443.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time