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Apocrine carcinoma of the vulva. Case report and review of literature

  • N. Alayón Hernández1,*,
  • J. Terrón Barroso1
  • R. Sotelo Avilés1
  • J. Aneiros-Fernández2
  • V. Crespo Lora3

1Department of Obstetrics and Gynaecology, San Cecilio University Hospital (HUSC), Granada, Spain

2Department of Pathology, Virgen de las Nieves University Hospital (HVN), Granada, Spain

3Department of Pathology, San Cecilio University Hospital (HUSC), Granada, Spain

DOI: 10.12892/ejgo3073.2016 Vol.37,Issue 5,October 2016 pp.722-725

Published: 10 October 2016

*Corresponding Author(s): N. Alayón Hernández E-mail: nicolasalayonh@gmail.com

PDF (1.6 MB)

Abstract

Objectives: To report a case of apocrine adenocarcinoma of the vulva and introduce the sentinel node dissection as a method to diagnose it. Materials and Methods: Description of a case of a 77-year-old woman with histological diagnostic of apocrine adenocarcinoma of the vulva and literature review of the 16 cases published from 1954 to nowadays. Results: Treatment of vulvar apocrine carcinoma is controversial given its low incidence and the small number of cases which have been reported. Conclusion: Selective sentinel lymph node biopsy may provide a valid option in selected patients to decrease their clinical complications.

Keywords

Apocrine carcinoma; Vulva; Sentinel node biopsy.

Cite and Share

N. Alayón Hernández,J. Terrón Barroso,R. Sotelo Avilés,J. Aneiros-Fernández,V. Crespo Lora. Apocrine carcinoma of the vulva. Case report and review of literature. European Journal of Gynaecological Oncology. 2016. 37(5);722-725.

URL:

https://www.ejgo.net/articles/10.12892/ejgo3073.2016

References

[1] Piura B., Gemer O., Rabinovich A., Yanai-Inbar I.: “Primary breast carcinoma of the vulva: case report and review of literature”. Eur. J. Gynaecol. Oncol., 2002, 23, 21.

[2] Alsaad K.O., Obaidat N., Dube V., Chapman W., Ghazarian D.: “Vulvar apocrine adenocarcinoma: a case with nodal metastasis and intranodal mucinous differentiation”. Pathol. Res. Pract., 2009, 205, 131.

[3] Dietel M., Bahnsen J., Stegner H.E., Hölzel F.: “Paget´s disease of the vulva with underlying apocrine adenocarcinoma and local lymph node invasion”. Pathol. Res. Pract., 1981, 171, 353.

[4] Goldstein R., Stefanato C.M., Warbey V.: “Advanced vulvar apocrine carcinoma expressing estrogen receptors that responds to tamoxifen therapy”. Future Oncol., 2012, 8, 1199.

[5] Bagwan I.N., Taylor A., Dina R.: “Metastatic apocrine carcinoma of female genital tract”. J. Clin. Pathol., 2009, 62, 287.

[6] Nazário A.C., Noronha Pde A., Salomão C., de Lima G.R.: “Apocrine gland cell carcinoma of the vulva. Report of a case”. Rev. Paul. Med., 1989, 107, 122.

[7] Van der Zee A.G., Oonk M.H., De Hullu J.A., Ansink A.C., Vergote I., Verheijen R.H., et al.: “Sentinel node dissection is safe in the treatment of early-stage vulvar cancer”. J. Clin. Oncol., 2008, 26, 884.

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