Article Data

  • Views 542
  • Dowloads 142

Original Research

Open Access

Comparison of the histopathological results of the endometrial thickness detected by transvaginal ultrasound of symptomatic and asymptomatic postmenopausal women

  • İ. Ulu1,*,
  • A. Çelik2
  • B. Haliloğlu2
  • E. İlter2
  • A. Midi3

1Department of Obstetrics and Gyneacology, Ümraniye Medical and Research Hospital, Istanbul, Turkey

2Department of Obstetrics and Gyneacology, Maltepe University Hospital, Istanbul, Turkey

3Department of Pathology, Maltepe University Hospital, Istanbul, Turkey

DOI: 10.12892/ejgo3093.2016 Vol.37,Issue 4,August 2016 pp.474-477

Published: 10 August 2016

*Corresponding Author(s): İ. Ulu E-mail: dripekulu@gmail.com

Abstract

Objective: The purpose of the study was to assess the reliability of transvaginal ultrasound (TVUSG) in endometrial pathologies by comparing the ultrasonographic and histopathologic findings in symptomatic and asymptomatic postmenopausal women. Materials and Methods: In this retrospective study the data of 129 postmenopausal women that underwent dilatation and curettage was reviewed by dividing them two groups as symptomatic and asymptomatic. Symptomatic group was divided into subgroups according to the value of endometrial thickness obtained by TVUSG. Results: Among all subjects the cancer rate was found statistically 3.043 times higher in patients with the endometrial thickness of 15 mm and greater and atrophic endometrium rate was 75% in patients with the endometrial thickness of less than five mm. Endometrial thickness was found significantly higher in cancer patients than the others (p < 0.05). Among the patients with endometrial thickness of 15 mm and greater, the cancer rate was found higher in symptomatic group than in the asymptomatic group. The cancer rate was found statistically higher in patients with bleeding compared to asymptomatic ones with the endometrial thickness between 5-14.99 mm (p < 0.05). Cancer was not detected in any of the symptomatic patients with the endometrial thickness of less than five mm. Conclusion: Postmenopausal patients with the symptom of bleeding should undergo detailed gynecological and ultrasonographic examination. The authors believe that this study may be a strong support to the success of TVUSG as a screening method in both symptomatic and asymptomatic postmenopausal women. Furthermore if the patient is symptomatic with a thick endometrium, to exclude the malignancy, endometrial biopsy must be performed.

Keywords

Postmenopausal bleeding; Transvaginal ultrasonography; Endometrial thickness; Endometrium cancer; Menopause.

Cite and Share

İ. Ulu,A. Çelik,B. Haliloğlu,E. İlter,A. Midi. Comparison of the histopathological results of the endometrial thickness detected by transvaginal ultrasound of symptomatic and asymptomatic postmenopausal women. European Journal of Gynaecological Oncology. 2016. 37(4);474-477.

References

[1] Siegel R., Ward E., Brawley O., Jemal A.: “Cancer statistics, 2011”. CA Cancer J. Clin., 2011, 61, 212.

[2] Karlsson B., Granberg S., Wikland M., Ylöstalo P., Kiserud T., Marsal K., et al.: “Transvaginal ultrasonography of endometrium in women with postmenopausal bleeding: a Nordic multi-center study”. Am. J. Obstet. Gynecol., 1995, 172, 1488.

[3] Chin-Yuan Hsu, Chih-Ping Chen, Kung-Liahng Wang.: “Assessment of postmenopausal bleeding”. International Journal of Gerontology,2008, 2, 55.

[4] Alfhaily F., Ewies A.A.: “The first line investigation of postmenopausal bleeding: transvaginal ultrasound scanning and endometrial biopsy may be enough”. Int. J. Gynecol. Cancer, 2009, 19, 892.

[5] Gambacciani M., Monteleone P., Ciaponi M., Sacco A., Genazzani A.R.: “Clinical usefulness of endometrial screening by ultrasound in asymptomatic postmenopausal women”. Maturitas, 2004, 48, 421.

[6] Kurjak A., Kupesic S.: “Overian senescence and its significance on uterin and ovarian perfusion”. Fertil. Steril., 1995, 64, 532.

[7] Gull B., Karlsson B., Milsom I., Granberg S.: “Can ultrasound replace dilation and curettage? A longitudinal evaluation of postmenopausal bleeding and transvaginal sonographic measurement of the endometrium as predictors of endometrial cancer”. Am. J. Obstet. Gynecol., 2003, 188, 401.

[8] Haller H., Matecjcić N., Rukavina B., Krasević M., Rupcić S., Mozetic D.: “Transvaginal sonography and hysteroscopy in women withpostmenopausal bleeding”. Int. J. Gynaecol. Obstet., 1996, 54, 155.

[9] Goldstein S.R.: “Significance of incidentally thick endometrial echo on transvaginal ultrasound in postmenopausal women”. Menopause, 2011, 18, 434.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top