Article Menu

Export Article

More by Authors Links

Article Data

  • Views 2355
  • Dowloads 166

Case Reports

Open Access

Benign metastasizing leiomyoma of bone and lung in postmenopausal women: two rare case reports and review of the literature

  • Y. Cirak1,*,
  • Ö.N. Sever2
  • Y. Urun2

1Department of Medical Oncology,Bursa Medicalpark Hospital, Bahcesehir University School of Medicine, Istanbul, Turkey

2Department of Medical Oncology, Dr. Ersin Arslan State Hospital, Gaziantep, Turkey

DOI: 10.12892/ejgo3341.2017 Vol.38,Issue 1,February 2017 pp.118-121

Published: 10 February 2017

*Corresponding Author(s): Y. Cirak E-mail: yalcincrk@gmail.com

PDF (584.23 kB) View Full-text

Abstract

Benign metastasizing leiomyoma (BML) is a rare disease that mostly occurs in women of reproductive age. Patients usually have a history of uterine leiomyoma and/or myomectomy. Although lung is the most common site of metastasis, bone involvement is rarely occurred. Here the authors report two rare cases of BML with lung and bone metastasis in postmenopausal women that were successfully treated with surgery and anti-estrogen approach.

Keywords

Benign metastasizing leiomyoma; Lung metastasis; Aromatase inhibitors.

Cite and Share

Y. Cirak,Ö.N. Sever,Y. Urun. Benign metastasizing leiomyoma of bone and lung in postmenopausal women: two rare case reports and review of the literature. European Journal of Gynaecological Oncology. 2017. 38(1);118-121.

URL:

https://www.ejgo.net/articles/10.12892/ejgo3341.2017

References

[1] Awonuga A.O., Shavell V.I., Imudia A.N., Rotas M., Diamond M.P., Puscheck E.E.: “Pathogenesis of benign metastasizing leiomyoma: a review”. Obstet. Gynecol. Surv., 2010, 65, 189.

[2] Laughlin S.K., Schroeder J.C., Baird D.D.: “New directions in the epidemiology of uterine fibroids”. Semin. Reprod. Med., 2010, 28, 204.

[3] Kayser K., Zink S., Schneider T., Dienemann H., André S., Kaltner H., et al.: “Benign metastasizing leiomyoma of the uterus: documentation of clinical, immunohistochemical and lectin-histochemical data of ten cases”. Virchows Arch., 2000, 437, 284.

[4] Rivera J.A., Christopoulos S., Small D., Trifiro M.: “Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature”. J. Clin. Endocrinol. Metab., 2004, 89, 3183.

[5] Steiner P.E.: “Metastasizing fibroleiomyoma of the uterus: Report of a case and review of the literature”. Am. J. Pathol., 1939, 15, 89.

[6] Funakoshi Y., Sawabata N., Takeda S., Hayakawa M., Okumura Y., Maeda H.: “Pulmonary benign metastasizing leiomyoma from the uterus in a postmenopausal woman: report of a case”. Surg. Today, 2004, 34, 55.

[7] Bell S.W., Kempson R.L., Hendrickson M.R.: “Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases”. Am. J. Surg. Pathol., 1994, 18, 535.

[8] Patton K.T., Cheng L., Papavero V., Blum M.G., Yeldandi A.V., Adley B.P., et al.: “Benign metastasizing leiomyoma: clonality, telomere length and clinicopathologic analysis”. Mod. Pathol., 2006, 19, 130.

Submission Turnaround Time

Top