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Original Research

Open Access

Decreased prevalence of high-risk human papillomavirus infection is associated with obesity

  • U. S. Jung1
  • J. S. Choi2,*,
  • J. H. Ko2
  • J. H. Lee3
  • S. Y. Park3
  • S. H. Park4

1Department of Obstetrics and Gynecology, Konyang University Hospital, Konyang University College of Medicine, Daejon

2Department of Obstetrics and Gynecology, Hanyang University College of Medicine, Seoul

3Department of Obstetrics and Gynecology, Sungkyunkwan University School of Medicine, Seoul

4Dr. Park’s Ob & Gyn Clinic, Seoul (Republic of Korea).

DOI: 10.12892/ejgo340113 Vol.34,Issue 1,January 2013 pp.70-74

Published: 10 January 2013

*Corresponding Author(s): J. S. Choi E-mail: choiyjjy1@hanyang.ac.kr

Abstract

Purpose of investigation: Obesity is correlated with low education, low economic status, and lower rates of Pap smears, which are known as socio-demographic risk factors for cervical cancer. However, the association between obesity and high-risk human papillomavirus (HR-HPV) infection, the necessary cause of cervical cancer, and its related precursors, is not established. Materials and Methods: The authors examined the association between obesity and HR-HPV infection in 6,868 patients, who participated in annual health examinations at the Kangbuk Samsung Hospital in Seoul, Korea, from January through December 2007. Results: The prevalence of HR-HPV infection was 14.8%. Women infected with HR-HPV had a lower body mass index (BMI), when compared with non-infected women. After adjustment for alcohol intake, cigarette smoking, and marital status, HR-HPV infection was found to be negatively associated with BMI. When the analysis was stratified according to BMI, the risk of HR-HPV infection was significantly lower among those who were overweight (OR = 0.817, 95% CI = 0.680 – 0.982), or obese (OR = 0.688, 95% CI = 0.556 – 0.851), when compared with women with normal weight. Conclusion: HR-HPV infection was associated with obesity defined by BMI, with a lower prevalence of infection observed in obese women.

Keywords

HPV; Obesity; Risk factor; Prevalence

Cite and Share

U. S. Jung, J. S. Choi,J. H. Ko,J. H. Lee,S. Y. Park,S. H. Park. Decreased prevalence of high-risk human papillomavirus infection is associated with obesity. European Journal of Gynaecological Oncology. 2013. 34(1);70-74.

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