Article Data

  • Views 197
  • Dowloads 109

Case Reports

Open Access

Atypical polypoid adenomyoma mixed with endometrioid carcinoma: a case report

  • L. Nejkovic′1,*,
  • V. Pazˇin1
  • D. Filimonovic′1

1University of Belgrade, School of Medicine, Clinic of Gynecology and Obstetrics “Narodni Front”, Belgrade (Serbia)

DOI: 10.12892/ejgo340121 Vol.34,Issue 1,January 2013 pp.101-103

Published: 10 January 2013

*Corresponding Author(s): L. Nejkovic′ E-mail: lnejkovic@sbb.rs

Abstract

The following is a description of an extremely rare tumor of the uterus, malignant atypical polypoid adenomyoma (APA), admixed with well-differentiated endometroid carcinoma, in a 29-year-old patient previously treated for sterility in whom, due to the existence of a ten-millimeter sessile tumor on the uterine corpus, verified by transvaginal ultrasonography (TVUS), a hysteroscopic resection of the anomaly was performed. The patient underwent all requisite examinations and was referred to the malignant diseases panel for an examination and a decision on further treatment. As the patient wished to preserve fertility, the authors decided to continue performing regular controls at intervals of two to three months. The first subsequent control called for a TVUS examination or one using another imaging method, with a multiple endometrial biopsy with curettage of the endocervix. The results of the first examination promised that fertility could be preserved. Therapy with medroxyprogesterone acetate (MPA) in daily dosages of 200 to 500 mg was advised, which the patient intentionally did not take. A spontaneous desired pregnancy was verified following the first control.

Keywords

Atypical endometrial polipoid adenoma; Hysteroscopic resection; Fertility preservation.

Cite and Share

L. Nejkovic′,V. Pazˇin,D. Filimonovic′. Atypical polypoid adenomyoma mixed with endometrioid carcinoma: a case report. European Journal of Gynaecological Oncology. 2013. 34(1);101-103.

References

[1] Iori K., Kouji B., Megumi Y., Yusuke K., Arisa U., Asuka O. et al.: “Atipical polipoid adenomyoma ( APAM) of the uterine-relationship with endometrial cancer”. J. Cancer Therapy, 2011, 2, 458.

[2] Mazur M.T.: “Atypical polypoid adenomyoma of the endometrium”. Am. J. Surg. Pathol., 1981, 5, 473.

[3] Fukuda M., Sakurai N., Yamamoto Y., Taoka H., Asakawa Y., Kurasaki A. et al.: “Case of atypical polypoid adenomyoma that possibly underwent a serial progression from endometrial hyperplasia to carcinoma”. J. Obstet. Gynaecol. Res., 2011, 37, 468.

[4] Fukanaga M., Endo Y., Ushigome S., Ishikawa E., " Atypical polypoid adenomyomas of the uterus”. Histopathology, 1995, 27, 35.

[5] Maeda T., Tateishi U., Sasajima Y., Hasegawa T., Daisaki H., Arai Y., Sugimura K.: “Atypical polypoid adenomyoma of the uterusappearance on F-FDG PET/MRI Fused images”. Am. J. Roentgenol., 2006, 186, 320.

[6] Young R.H., Treger T., Scully E.: “Atypical polypoid adenomyoma of the uterus; a report of 27 cases”. Am. J. Clin. Pathol., 1986, 86, 139.

[7] Lee K.R.: “Atypical polypoid adenomyoma of the endometrium associated with adenomyomatosis and adenocarcinoma”. Gynecol. Oncol., 1993, 51, 416.

[8] Terada T.: “Atypical polypoid adenomyoma of the uterus: an immunohistochemical study on 5 cases”. Ann. Diagn. Pathol., 2011, 15, 338.

[9] Horita A., Kurata A., Maeda D., Fukayama M., Sakamoto A.: “Immunohistochemical characteristics of atypical polypoid adenomyoma with special reference to H-caldesmon”. Int. J. Gynecol. Pathol., 2011, 30, 64.

[10] Horita A., Kurata A., Komatsu K., Yajima M., Sakamoto A.: “Coexistent atypical polypoid adenomyoma and complex atypical endometrial hyperplasia in the uterus”. Diagn. Cytopathol., 2010, 38, 527.

[11] Longacre T. A., Chung H., Rouse R. V., Hendrickson M.R.: “Atypical polypoid adenomyofibromas (Atypical polypoid adenomyomas) of the uterus: a clinicopathologic study of 55 cases”. Am. J. Surg. Pathol., 1996, 20, 1.

[12] Di Spiezio Sardo A., Mazzon I., Gargano V., Di Carlo C., Guida M., Mignona C. et al.: “Hysteroscopic treatment of atypical polypoid adenomyoma diagnosed incidentally in young infertile woman”. Fertil. Steril., 2008, 89, 456. Epub 2007, Aug. 13.

[13] Clement P.B., Young R.H.: “Atypical polypoid adenomyoma of the uterus associated with Turner’s Syndrome: a report of three cases, including a review of estrogen-associated with Turner’s Syndrome”. Int. J. Gynecol. Pathol., 1987, 6, 104.

[14] Nasu K., Miyazaki T., Takai N., Miyakawa I.: “Atypical polypoid adenomyoma in patinet with hyperprolactinemia”. Int. Gynecol. Cancer, 2001, 11, 326.

[15] Burke C., Kelehan P., Wingfield M.: “Unsuspected endometrial pathology in subfertile woman”. Ir. Med. J., 2007, 100, 466.

[16] Sugiyama T., Ohta S., Nishida T., Okura N., Tanabe K., Yakushiji M.: “Two cases of endometrial adenocarcinoma arising from atypical polypoid adenomyoma”. Gynecol. Oncol., 1998, 71, 141.

[17] Baschinsky D., Keyhani-Rofagha S., Hameed A.: "Exfoliative cytology of atypical polypoid adenomyoma, a case report". Acta Cytologica, 1999, 43, 637.

[18] Dinas K., Daniilidis A., Drizis E., Zarabouks T., Tzafettas J.: “Incidental diagnosis of atypical polypoid adenomyoma in young infertile woman”. Eur. J. Gynaecol. Oncol., 2009, 30, 701.

[19] Yahata T., Nonaka T., Watanabe A., Sekine M., Tanaka K.: “Complete hysterosopic resection of large atypical polypoid adenomyoma, followed by a successful pregnancy”. Fertil. Steril., 2011, 95, 2435.

[20] Clouqueur E., Lucot J.P., Collinet P., Farine M.O., Kedraon O., Poncelet E.: “Atypical polypoid adenomyoma”. Gynecol. Obstet. Fertil., 2012, epub a head of print.

[21] Wong A.Y., Chan K.S., Lau W.L.,Tang L.C.: “Pregnancy outcome of patient with atypicalpolypoid adenomyoma”. Fertil. Steril., 2007, 88, 7.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top