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Case Reports
Open AccessChemotherapy-induced differentiation to cure botryoid rhabdomyosarcoma: a case report and review of the literature
Chemotherapy-induced differentiation to cure botryoid rhabdomyosarcoma: a case report and review of the literature
- T. Assi1,*,
- E. El Rassy1
- G. Abi-Tayeh2
- C. Sader-Ghorra3
- G. Abadjian3
- R. Eid1
- T. Moussa4
- F. Farhat1
- J. Kattan1
1Department of Hematology-Oncology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
2Department of Obstetrics and Gynecology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
3Department of Pathology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
4Department of Radiology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
*Corresponding Author(s): T. Assi E-mail: tarekassi@gmail.com
Abstract
Rhabdomyosarcoma (RMS) occurs rarely in adults and constitutes 2-6% of all uterine neoplasms. The authors report the case of a 26-year-old woman diagnosed with botryoid RMS that presented discordant progression results on follow up imaging and cytodifferentiation on pathologic control. This case showed that radiological evaluation could be misleading as the tumor demonstrated chemotherapy-induced differentiation without volume reduction. This case illustrates the limitations of using the imaging anatomical dimensions of sarcomas for treatment planning and highlights the potential role of functional imaging to assess the response to treatment.
Keywords
Chemotherapy; Botryoid rhabdomyosarcoma; Cervix; Cytodifferentiation.
Cite and Share
T. Assi, E. El Rassy, G. Abi-tayeh, C. Sader-ghorra, G. Abadjian, R. Eid, T. Moussa, F. Farhat, J. Kattan. Chemotherapy-induced differentiation to cure botryoid rhabdomyosarcoma: a case report and review of the literature. European Journal of Gynaecological Oncology. 2017; 38(2): 323-325. doi: 10.12892/ejgo3554.2017
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