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Umbilical metastasis of an endometrial carcinoma (Sister Mary Joseph’s nodule): a case report and review of literature
1Deparment of Obstetrics and Gynecology, Izmir University Hospital, Izmir
2Izmir Oncology Center, Izmir
3Private Clinic of Gynecology and Oncology, Izmir (Turkey)
*Corresponding Author(s): M. Bicer E-mail: mervebicermd@gmail.com
Introduction: Umbilical metastasis from intra-abdominal or pelvic malignancies which is also known as “Sister Mary Joseph’s nodule” (SMJN) is a rare entity and typically described in cases of gastric carcinoma. However, even fewer than 30 cases with umbilical metastasis originated from endometrial cancer is reported in previous literature. Here the authors report a new case of SMJN originating from endometrial carcinoma. Case Report: A 57-year- old woman was diagnosed with endometrial carcinoma and umbilical mass. Total hysterectomy, bilateral salpingo-oophorectomy, lymph node dissection, and umbilical mass resection were performed. The umbilical mass was identified as a metastasis from endometrial cancer. Conclusion: In conclusion, this case showed that, taking the rarity of umbilical metastasis from endometrial carcinoma into consideration, it is difficult to recognize, and differential diagnosis is important in terms of choosing the adequate treatment.
Endometrial carcinoma; Umbilical metastasis; SMJN.
M. Bicer,E. Ozkan,A. Baloglu. Umbilical metastasis of an endometrial carcinoma (Sister Mary Joseph’s nodule): a case report and review of literature. European Journal of Gynaecological Oncology. 2017. 38(4);642-644.
[1] Touraud J.P., Lentz N., Dutronc Y., Mercier E., Sagot P., Lambert D.: “Umbilical cutaneous metastasis (or Sister Mary Joseph’s nodule) disclosing an ovarian adenocarcinoma”. Gynecol. Obstet. Fertil., 2000, 28, 719.
[2] Piura B., Meirovitz M., Bayme M., Shaco-Levy R.: “Sister Mary Joseph’s nodule originating from endometrial carcinoma incidentally detected during surgery for an umbilical hernia: a case report”. Arch. Gynecol. Obstet., 2006, 274, 385.
[3] Brustman L., Selter V.: “Sister Joseph’s nodule. Seven cases of umbili cal metastases from gynecologic malignancies”. Gynecol. Oncol., 1984, 19, 155.
[4] Majmudar B., Wiskind A.K., Croft B.N., Dudley A.G.: “The Sister (Mary) Joseph nodule. Its significance in gynecology”. Gynecol. Oncol., 1991, 10, 152.
[5] Dubreuil A., Dompmartin A., Barjot P., Louvet S., Leroy D.: “Umbilical metastasis or Sister Mary Joseph‘s nodule”. Int. J. Dermatol., 1998, 37, 70.
[6] Galvan V.G.: “Sister Mary Joseph’s nodule”. Ann. Intern. Med., 1998, 128, 410.
[7] Ikeda S.I., Yajima M., Hida K., Hattori M., Shimizu S., Umezaki I., et al.: “Sister Joseph umbilical nodule coexisting with endomeriosis from endometrial carcinoma”. Arch. Gynecol. Obstet., 2006, 273, 250.
[8] Hertel H., Fleck M., Kuhne-Heid R., Schneider A.: “Trocar-site metastasis is not always due to laparoscopy”. Surg. Endosc., 2001, 15, 896.
[9] Ivanova V., Karaivanov M., Marinov E., Gorchev G., Raicheva S.: “Umbilical metastasis—‘‘Sister Joseph’s nodule’’ of an endometrial adenocarcinoma: a case report and review of the literature”. Akush. Ginekol. (Sofia), 2001, 40, 33.
[10] Gabriele R., Conte M., Egidi F., Borghese M.: “Umbilical metastases: current viewpoint”. World J. Surg. Oncol., 2005, 3, 13,
[11] Levine D., Miller S., Al-Dawsari N., Barak O., Gottlieb A.B.: “Paraneoplastic dermatoses associated with gynecologic and breast malignancies”. Obstet. Gynecol. Surv., 2010, 65, 455.
[12] Samaila M.O, Adesiyun A.G, Waziri G.D, Koledade K.A, Kolawole A.O.: “Cutaneous umbilical metastases in post-menopausal females with gynaecological malignancies”. J. Turk. Ger. Gynecol. Assoc., 2012, 13, 204.
[13] Bailey H.: “Demonstrations of physical signs in clinical surgery. 11th ed. Baltimore: Williams & Wilkins, 1949, 227.
[14] Powell J.L.: “Powell’s pearls: eponyms in medical and surgical history. Sister Joseph’s nodule; Sister Mary Joseph (1856–1939)”. J. Surg. Educ., 2011, 68, 442.
[15] Barrow M.V.: “Metastatic tumours of the umbilicus”. J. Chron. Dis., 1966, 19, 1113.
[16] Reingold I.M.: “Cutaneous metastases from internal carcinoma”. Cancer, 1966, 19, 162.
[17] Papalas J.A., Selim M.A.: “Metastatic vs primary malignantneoplasms affecting the umbilicus: clinicopathologic features of 77 tumors”. Ann. Diagn. Pathol., 2011, 15, 237.
[18] Sugarbaker P.H.: “Sister Mary Joseph’s sign”. J. Am. Coll. Surg., 2001, 193, 339.
[19] Nolan C., Semer D.: “Endometrial cancer diagnosed by Sister Mary Joseph nodule biopsy: Case report”. Gynecol. Oncol. Case Rep., 2012, 2, 110.
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