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Case Reports

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Ovarian mucinous tumor with anaplastic carcinoma and sarcoma-like mural nodule: about a difficult case

  • F. Lai-Tiong1,*,

1Institut de Cancérologie du Gard, Rue du Professeur Henri Pujol, Nîmes (France)

DOI: 10.12892/ejgo3665.2017 Vol.38,Issue 4,August 2017 pp.618-620

Published: 10 August 2017

*Corresponding Author(s): F. Lai-Tiong E-mail: florencelt@hotmail.fr

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Abstract

Development of mural nodules in mucinous or serous ovarian tumors are exceptional. These nodules can be benign or malignant. The author reports the seventh case of mucinous ovarian tumor associated with both sarcoma-like mural nodules and anaplastic carcinoma, in a 58-year-old, post-menopausal Caucasian female. The patient underwent surgery, followed by adjuvant chemotherapy for a pT1aN0 lesion. Shortly after completion of chemotherapy, diffuse metastases appeared. Second-line chemotherapy by anthracyclin was administered. After one cycle, disease progression with ascites was observed. Third-line chemotherapy by gemcitabine was decided. The prognosis of these tumors is poor, depending on the characteristics of the mural nodule. No consensus for treatment exists after surgery.

Keywords

Mucinous ovarian tumor; Sarcoma-like mural nodule; Anaplastic carcinoma.


Cite and Share

F. Lai-Tiong. Ovarian mucinous tumor with anaplastic carcinoma and sarcoma-like mural nodule: about a difficult case. European Journal of Gynaecological Oncology. 2017. 38(4);618-620.

URL:

https://www.ejgo.net/articles/10.12892/ejgo3665.2017

References

[1] Park T.C., Lee H.N., Shin O.R., Lee K.H.: “A case of a borderline mucinous tumor of the ovary with sarcoma-like mural nodules producing granulocyte colony-stimulating factor”. Eur. J. Gynaecol. Oncol., 2012, 33, 526.

[2] Jinfeng Z., Ming G., Peifeng L., Yi L., Yongcheng C.: “Ovarian mucinous cystic tumor with sarcoma-like mural nodules and multifocal anaplastic carcinoma: a case report”. Int. J. Clin. Exp. Pathol., 2013, 6, 1688.

[3] Prat J., Scully R.E.: “Ovarian mucinous tumors with sarcoma-like mural nodules: a report of seven cases”. Cancer, 1979, 44, 1332.

[4] Gungor T., Altinkaya S.O., Akbay S., Bilge U., Mollamahmutoglu L.: “Malignant mural nodules associated with serous ovarian tumor of borderline malignancy: a case report and literature review”. Arch. Gynecol. Obset., 2010, 281, 485.

[5] Allende D.S., Drake R.D., Chen L.: “Muralnodules of clear cell carcinoma in a mucinous borderline tumor of the ovary: a case report”. Pathol. Res. Int., 2010, 2010, 438534.

[6] Prat J., Scully R.E.: “Ovarian mucinous tumors with sarcoma-like mural nodules: a report of seven cases”. Cancer, 1979, 44, 1332.

[7] Fujii S., Konishi I., Kobayashi F., Okamura H., Yamabe H., Mori T.: “Sarcoma-like mural nodules combined with a microfocus of anaplastic carcinoma in mucinous ovarian tumor”. Gynecol. Oncol., 1985, 20, 219.

[8] Nichols G.E., Mills S.E., Ulbright T.M., Czernobilsky B., Roth L.M.: “Spindle cell mural nodules in cystic ovarian mucinous tumors. A clinicopathologic and immunohistochemical study of five cases”. Am. J. Surg. Pathol., 1991, 15, 1055.

[9] Bagué S., Rodriguez I.M., Prat J.: “Sarcoma-like mural nodules in mucinous cystic tumors of the ovary revisited: a clinicopathologic analysis of 10 additional cases”. Am. J. Surg. Pathol., 2002, 26, 1467.

[10] Chang W.C., Sheu B.C., Lin M.C., Chow S.N., Huang S.C.: “Carcinosarcoma-like mural nodule in intestinal-type mucinous ovarian of borderline malignancy: a case report”. Int. J. Gynecol. Cancer, 2005, 15, 549.

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