Perforated ovarian low-grade endometrioid adenocarcinoma: a case-report

Most grade 1 endometrioid cancers are confined at the time of diagnosis and confer a good prognosis. The author reports the case of a 46-year-old Caucasian woman, referred to the gynecologist for anemia and increased volume of the abdomen. Computed tomography scan showed a large intra-abdominal cystic mass, originating from ovary. The tumor measured 22 cm and was perforated. The patient underwent radical surgery. Histology confirmed epithelial tumor type endometrioid, very good differentiated, grade 1 adenocarcinoma. Adjuvant chemotherapy was administered. At 12 months post-presentation, imaging did not show any sign of recurrence and the patient remains under surveillance.

Endometrioid; Adenocarcinoma; Perforated tumor; Chemotherapy.

[1] Wagner B.J., Buck J.L., Seidman J.D., Mc Cabe K.L.: “From the archives of the AFIP. Ovarian epithelial neoplasms: radiologic-pathologic correlation”. Radiographics, 1994, 14, 1351.

[2] Kumar V., Abbas A.K., Fausto N., Aster J.C.: “Robbins and Cotran pathologic basis of disease”. Philadelphia: W.B. Saunders Co., 2005.

[3] Jung S.E., Lee J.M., Rha S.E., Byun J.Y., Jung J.I., Hahn S.T.: “CT and MR imaging of ovarian tumors with emphasis on differential diagnosis”. Radiographics, 2002, 22, 1305.

[4] Tanaka Y.O., Yoshizako T., Nishida M., Yamaguchi M., Sugimura K., Itai Y.: “Ovarian carcinoma in patients with endometriosis: MR imaging findings”. AJR Am. J. Roentgenol., 2000, 175, 1423.

[5] Storey D.J., Rush R., Stewart M., Rye T., Al Nahun A., Williams A.R. et.al.: “Endometrioid epithelial ovarian cancer: 20 years of prospectively collected data from a single center”. Cancer, 2008, 112, 2211.

[6] De Breuck Y., Ramboer K., Ghekiere J., Oosterlinck D., Ghiteko J., Van Hoe L., et al.: “Endometrioid cystadenocarcinoma of the ovary”. J. Belge. Radiol., 1996, 79, 165.