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Original Research

Open Access

Prevalence of pulmonary embolism in gynecological cancer: the experience of a single tertiary center in Okinawa, Japan

  • M. Kozaki1
  • T. Ooyama1
  • W. Kudaka1
  • T. Nakamoto1
  • A. Wakayama1
  • Y. Aoki1,*,

1Departments of Obstetrics and Gynecology, Graduate School of Medicine, University of the Ryukyus, Okinawa (Japan)

DOI: 10.12892/ejgo3898.2018 Vol.39,Issue 1,February 2018 pp.44-48

Published: 10 February 2018

*Corresponding Author(s): Y. Aoki E-mail: yoichi@med.u-ryukyu.ac.jp

Abstract

Purpose: To explore the incidence and outcome of pulmonary embolism (PE) cases in Japanese patients with gynecological malignancy. Materials and Methods: The authors reviewed the medical charts of all patients with gynecological malignancy who had a diagnosis of PE at this Hospital between January 2008 and December 2013. Results: Twenty patients developed PE during the study period. Nineteen patients had advanced or recurrent cancer. The incidence of PE was 1.8%, and those with ovarian, cervical, uterine corpus, and vulvar cancers were 7.5%, 0.86%, 1.0%, and 7.7%, respectively. PE developed in 12 patients before cancer treatment, six during chemotherapy, and two postoperatively. Three patients died as a result of PE. Conclusion: PE more frequently occurred in patients with ovarian and vulvar cancers, and those with advanced/recurrent disease. Patients with active gynecological cancer require thromboprophylaxis throughout hospitalization and not just in the perioperative period, and should be periodically assessed for venous thromboembolism risk.

Keywords

Pulmonary embolism; Deep vein thrombosis; Gynecological cancer.

Cite and Share

M. Kozaki,T. Ooyama,W. Kudaka,T. Nakamoto,A. Wakayama,Y. Aoki. Prevalence of pulmonary embolism in gynecological cancer: the experience of a single tertiary center in Okinawa, Japan. European Journal of Gynaecological Oncology. 2018. 39(1);44-48.

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