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Original Research

Open Access

Prevalence of HPV and genotype distribution in “catch-up” HPV vaccinated women


  • M. Grigore1,*,
  • M. Matei2
  • A. Pristavu1
  • D. Jitaru3
  • I. Teleman4

1Department of Obstetrics and Gynaecolog, Iasi (Romania)y

2Department of Epidemiology, Iasi (Romania)

3Department of Biochemistry, Iasi (Romania)

4Department of Pathology,University of Medicine and Pharmacy “Grigore T.Popa”, Iasi (Romania)

DOI: 10.12892/ejgo3980.2018 Vol.39,Issue 5,October 2018 pp.760-763

Published: 10 October 2018

*Corresponding Author(s): M. Grigore E-mail: mihaela.grigore@edr.ro

Abstract

Purpose of investigation: The aim of the present study was to evaluate the prevalence of HPV and genotype distribution among HPVvaccinated women. Material and Methods: The authors recruited 147 women, which were vaccinated through “catch-up vaccination”, five years before this study. The authors analyzed the presence of HPV, genotype distribution, and risk factors for HPV infections. Results: The relative prevalence of HPV/DNA was as follows: out of the total 147 tested samples, 19 samples (12.92%) were positive for HPV/DNA, 11 of which (7.48%) were single type HPV infections, and eight (5.44%) tested positive for multiple HPV genotypes. The most frequent genotypes were: 16, followed by 35, 56, and 31. Low risk genotypes 6 and 11 were present together in one case. Conclusion: The results showed a decrease in HPV prevalence 16/18 in vaccinated women through a catch-up vaccination, suggesting good effects of the previous HPV immunization program.

Keywords

HPV infection; HPV vaccine; “Catch-up” vaccination.

Cite and Share

M. Grigore,M. Matei,A. Pristavu,D. Jitaru,I. Teleman. Prevalence of HPV and genotype distribution in “catch-up” HPV vaccinated women. European Journal of Gynaecological Oncology. 2018. 39(5);760-763.

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