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Prevalence of HPV and genotype distribution in “catch-up” HPV vaccinated women
1Department of Obstetrics and Gynaecolog, Iasi (Romania)y
2Department of Epidemiology, Iasi (Romania)
3Department of Biochemistry, Iasi (Romania)
4Department of Pathology,University of Medicine and Pharmacy “Grigore T.Popa”, Iasi (Romania)
*Corresponding Author(s): M. Grigore E-mail: mihaela.grigore@edr.ro
Purpose of investigation: The aim of the present study was to evaluate the prevalence of HPV and genotype distribution among HPVvaccinated women. Material and Methods: The authors recruited 147 women, which were vaccinated through “catch-up vaccination”, five years before this study. The authors analyzed the presence of HPV, genotype distribution, and risk factors for HPV infections. Results: The relative prevalence of HPV/DNA was as follows: out of the total 147 tested samples, 19 samples (12.92%) were positive for HPV/DNA, 11 of which (7.48%) were single type HPV infections, and eight (5.44%) tested positive for multiple HPV genotypes. The most frequent genotypes were: 16, followed by 35, 56, and 31. Low risk genotypes 6 and 11 were present together in one case. Conclusion: The results showed a decrease in HPV prevalence 16/18 in vaccinated women through a catch-up vaccination, suggesting good effects of the previous HPV immunization program.
HPV infection; HPV vaccine; “Catch-up” vaccination.
M. Grigore,M. Matei,A. Pristavu,D. Jitaru,I. Teleman. Prevalence of HPV and genotype distribution in “catch-up” HPV vaccinated women. European Journal of Gynaecological Oncology. 2018. 39(5);760-763.
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