Two unusual cases: vulvar lipoma - description of the largest case in literature. Developing myoma with the longest pedicle

The authors present two cases of benign tumors one located on the outer surface of the vulva, and the second extending beyond the vagina. The first, originating from the right pudendal lip, a lipoma measuring 23 cm in greatest diameter, weighing 6.6 kg, and the second a pedunculated, uterine smooth muscle myoma with a pedicle of 6.5 cm, maximum diameter 18 cm, weight 700 grams, which caused significant metroptosis. Operative procedures in each case were free of complications.

Extremely large vulvar lipoma; Pedunculated giant uterine myoma.

[1] Xu Z., Zeng R., Liu J.: “A large primary retroperitoneal vaginal leiomyosarcoma: a case report”. J. Med. Case Rep., 2015, 9, 130.

[2] Khosla D., Patel F.D., Kumar R., Gowda K.K., Nijkawan R., Sharma S.C.: “Leiomyosarcoma of the vagina: A rare entity with comprehensive review of the literature”. Int. J. Appl. Basic Med. Res. 2014, 4, 128

[3] Chan MM., Yong T., Sittampalm K.: “Giant labial fibroepithelial stromal polyp”. Malays”. J. Pathol., 2013, 35, 91.

[4] Baiocchi G., Rocha R.M.: “Vulvar cancer surgery”. Curr. Opin. Obstet. Gynecol., 2014, 26, 9.

[5] Pantanowitz L., Henneberry J.M., Otis C.N., Zakhary M.: “Adenolipoma of the external female genitalia”. Int. J. Gynecol. Pathol., 2008, 27, 297.

[6] Lee J.H., Chung S.M.: “Large vulvar lipoma in an adolescent: a case report”. J. Korean. Med. Sci., 2008, 23, 744.

[7] Agarwal U., Dahiya P., Sangwan K.: “Vulval lipoma: a rare occurrence”. Arch. Gynecol. Obstet., 2004, 270, 59.

[8] Cheng C.C., Ho C.M., Liu C.Y.: “Atypical lipomatous tumors of the vulva”. Taiwan J. Obstet. Gynecol., 2011, 50, 379.

[9] Sengupta S., Bhattacharya M., Datta P.: “Angiolipoma of the labia majora”. J. Indian Med. Assoc., 1976, 66, 40.

[10] Reis-Filho J.S., Milanezi F., Soares M.F., Fillus-Neto J., Schmitt F.C.: “Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature”. J. Cutan. Pathol., 2002, 29, 59.

[11] Salam G.A.: “Lipoma excision”. Am. Fam. Physician, 2002, 65, 901

[12] Odoi A.T., Owusu-Bempah A., Dassah E.T., Darkey D.E., Quayson S.E.: “Vulvar lipoma: is it so rare?” Ghana Med. J., 2011, 45, 125.

[13] Coronil-Belloso P., Fariña-Pérez L.A., Picurelli-Oltra L., Peran- Teruel M., Lorenzo-Lorenzo D., Ares-Rodriguez X., et al.: “Large vulvar lipoma”. Actas Urol. Esp., 2013, 37, 594.

[14] Signorini M., Campiglio G.L. “Posttraumatic lipomas: where do they really come from?” Plast. Reconstr. Surg., 1998, 101, 699.

[15] Copcu E., Sivrioglu N.S.: “Posttraumatic lipoma: analysis of 10 cases and explanation of possible mechanisms”. Dermatol. Surg., 2003, 29, 215.

[16] Aust MC., Spies M., Kall S., Gohritz A., Boorboor P., Kolokythas P., Vogt P.M.: “Lipomas after blunt soft tissue trauma: are they real? Analysis of 31 cases”. Br. J. Dermatol., 2007, 157, 92.

[17] Ahram J., Lemus R., Schiavello H.J.: “Leiomyosarcoma of the vagina: case report and literature review”. Int. J. Gynecol. Cancer, 2006, 12, 884.

[18] Terzic M., Maricic S., Dotlic J. “Vaginal removal of very large nascent uterine myoma - case report and literature Review”. Geburtshilfe Frauenheilkd., 2013, 73, 724.

[19] Golan A., Zachalka N., Lurie S., Sagiv R., Glezerman M.: “Vaginal removal of prolapsed pedunculated submucous myoma: a short, simple, and definitive procedure with minimal morbidity”. Arch. Gynecol. Obstet., 2005, 271, 11.

[20] Stewart E.A.: “Uterine fibroids”. Lancet, 2001, 357, 293.

[21] Tsai H.J., Ruan C.V., Kok V.C., Li M.C.: “A large primary vaginal leiomyosarcoma diagnosed postoperatively and uterine leiomyomas treated with surgery and chemotherapy”. J. Obstet. Gynaceol., 2013, 33, 643.

[22] Ashraf Ganjooie T.: “Case report of vulvar liposarcoma”. J. Obstet. Gynaecol. Res., 2004, 30, 80.