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A case of delayed diagnosis of endometrial carcinoma due to a uterus didelphys
1Hospital Gelderse Vallei Ede, Ede, The Netherlands
*Corresponding Author(s): R.R. Aapkes E-mail: r.r.aapkes@gmail.com
In this case report, the authors present a patient with postmenopausal bleeding in whom diagnosis was delayed due to a uterus didelphys. Early diagnosis is important in endometrial carcinoma to ensure the highest possible chances of survival. In case of postmenopausal bleeding, physicians should be aware of the possibility of a uterus anomaly, especially in the presence of related congenital abnormalities as renal abnormalities. If there is any clinical suspicion of a uterus anomaly, such as uterus didelphys, further investigations such as MRI are needed and biopsies of both horns of the uterus are indicated.
Uterus anomaly; Müllerian duct anomaly; Uterus didelphys; Postmenopausal bleeding; Endometrial carcinoma.
R.r. Aapkes, R.a.k. Samlal. A case of delayed diagnosis of endometrial carcinoma due to a uterus didelphys. European Journal of Gynaecological Oncology. 2017; 38(5): 810-812. doi: 10.12892/ejgo4104.2017
[1] Jemal A., Bray F., Center M.M., Ferlay J., Ward E., Forman D.: “Global Cancer Statistics”. CA Cancer J. Clin., 2011, 61, 69.
[2] Creasman W.T., Odicino F., Maisonneuve P., Quinn M.A., Beller U., Benedet J.L. et al.: “Carcinoma of the corpus uteri. FIGO 26th annual report on the results of treatment in gynecological cancer.” Int. J. Gynaecol. Obstet., 2006, 95, S105.
[3] Kim H.H., Laufer M.R.: “Developmental abnormalities of the female reproductive tract.” Curr. Opin. Obstet. Gynecol., 1994, 6, 518.
[4] Chan Y.Y., Jayaprakasan K., Zamora J., Thorton J.G., et al.: “The prevalence of congenital uterine anomalies in unselected and highrisk populations: a systematic review.” Hum. Reprod. Update, 2011, 17, 761.
[5] Dreisler E., Stampe Sorenson S.: “Mullerian duct anomalies diagnosed by saline contrast sonohysterography: prevalence in general population.” Fertil. Steril., 2014, 102, 525.
[6] Grimbizis G.F., Camus M., Tarlatzis B.C., Bontis J.N., Devroey P.: “Clinical implications of uterine malformations and hysteroscopic treatment results.” Hum. Reprod. Update, 2001, 7, 161.
[7] Lin P.C., Bhatnagar K.P., Nettleton G.S., Nakajima ST.: “Female genital anomalies affecting reproduction.” Fertil. Steril., 2002, 78, 899.
[8] Oppelt P., von Have M., Paulsen M., Strissel P.L., Strick R., Brucker S., et al.: “Female genital malformations and their associated abnormalities.” Fertil. Steril. 2007, 87, 335.
[9] Fealy J., Nelson J.H.: “Adenocarcinoma in one-half of a uterus didelphys.” Med. Ann. Dist. Columbia, 1957, 26, 76.
[10] Siegler S.L.: “Adenocarcinoma in one horn of uterus didelphys.” Am. J. Obstet. Gynecol., 1950, 59, 162.
[11] Fly O.S., Pratt J.H.: “Carcinoma of the fundus occuring in double uterus. Report of three cases.” Am. J. Obstet. Gynecol., 1956, 72, 669.
[12] Dane C., Zeynap T., Dane B., Erqinbas M., Cetin A.: “A single horn endometrial carcinoma of a uterus bicornis unicollis.” J. Gynecol. Oncol., 2009, 20, 195.
[13] Olpin J.D., Heilbrun M.: “Imaging of Müllerian duct anomalies.” Top. Magn. Reson. Imaging, 2010, 21, 225.
[14] Pellerito J.S., McCarthy S.M., Doyle M.B., Glickman M.G., DeCherney A.H.: “Diagnosis of uterine anomalies: relative accuracy of MR imaging, endovaginal sonography, and hysterosalpingography.” Radiology, 1992, 183, 795.
[15] Voss M.A., Ganesan R., Ludeman L., McCarthy K., Gornall R., Schaller G., et al.: “Should grade endometrioid endometrial carcinoma be considered a type 2 cancer-a clinical and pathological evaluation.” Gynecol. Oncol., 2012, 124, 15.
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