A case report of placental site trophoblastic tumor with maxillofacial metastasis

The authors report a case of a placental site trophoblastic tumor (PSTT) in a 38-year-old Chinese woman eight years after a term delivery. The woman presented with abnormal vaginal discharge and underwent hysterectomy. The final diagnosis was confirmed by histological examinations in conjunction with immunohistochemical studies. However five weeks after hysterectomy, serum hCG concentration increased, which indicated recurrence of PSTT, therefore the patient was admitted and cured by four courses of EMA/CO. Five years later, the serum-hCG level increased again and the patient underwent a pulmonary lobectomy. The serum hCG concentration dropped and be kept to normal till a mass located in right maxillofacial was found one year later. After one year and two months , the patient received right maxillofacial hemangioma in her hometown hospital. The pathological report of PSTT is confirmed by the experts. After one cycle of EMA/EP chemotherapy, the patient died of multiple organ failure after nearly 8-year-long fight with PSTT.

Placental site trophoblastic tumor (PSTT); Diagnosis; Treatment; Fowllow-Up; Prognostic factor.

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