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Acute hyperglycemia following intraperitoneal irrigation with 5% dextrose in a patient with pseudomyxoma peritonei. A case report
1Department of Anesthesiology and Pain Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
2Department of Anesthesiology and Pain Medicine, Kyung Hee University Hospital at Gangdong, Seoul, South Korea
*Corresponding Author(s): Jong-Man Kang E-mail: kjm@khnmc.or.kr
Pseudomyxoma peritonei (PMP) is a mucinous tumor and rare disease. Surgical removal is basic treatment and peritoneal lavage with dextrose in water conducts for removing remnant. A 61-year-old woman was diagnosed PMP and underwent surgery. Despite initial serum glucose was 103 mg/dl, hyperglycemia (serum glucose 359 mg/dl) was detected after intraperitoneal irrigation with dextrose in water. She recovered breath, but mental state was unconscious. She was transferred to post-anesthesia care unit, in state of keeping of intubation. Insulin was infused, and serum glucose was 275 mg/dl. It took more than three hours to recover consciousness. Postoperatively, newly appeared QT interval prolongation and pleural effusion developed. Two weeks later, she was discharged without any sequelae. In conclusion, intraperitoneal dextrose irrigation might be related to intraoperative hyperglycemia, therefore the serum glucose monitoring and proper treatment during and after the intraperitoneal irrigation with dextrose are needed.
Depressed consciousness; Dextrose in water; Hyperglycemia; Pleural effusion; Pseudomyxoma peritonei; QT interval prolongation.
Hee Yong Kang,Su-Mi Lee,Seung-Beom Kim,Jong-Man Kang. Acute hyperglycemia following intraperitoneal irrigation with 5% dextrose in a patient with pseudomyxoma peritonei. A case report. European Journal of Gynaecological Oncology. 2018. 39(4);676-678.
[1] Smeenk R.M., Verwaal V.J., Zoetmulder F.A.: “Pseudomyxoma peritonei”. Cancer Treat Rev., 2007, 33, 138.
[2] Piver M.S., Lele S.B., Patsner B.: “Pseudomyxoma peritonei: possible prevention of mucinous ascites by peritoneal lavage”. Obstet. Gynecol., 1984, 64, 95S.
[3] Roy W.J. Jr., Thomas B.L., Horowitz I.R.: “Acute hyperglycemia following intraperitoneal irrigation with 10% dextrose in a patient with pseudomyxoma peritonei”. Gynecol. Oncol., 1997, 65, 360.
[4] Duckrow R.B., Beard D.C., Brennan R.W.: “Regional cerebral blood flow decreases during chronic and acute hyperglycemia”. Stroke, 1987, 18, 52.
[5] Cox D.J., Kovatchev B.P., Gonder-Frederick L.A., Summers K.H., McCall A., Grimm K.J., et al.: “Relationships between hyperglycemia and cognitive performance among adults with type 1 and type 2 diabetes”. Diabetes Care, 2005, 28, 71.
[6] Lipshutz A.K., Gropper M.A.: “Perioperative glycemic control: an evidence-based review”. Anesthesiology, 2009, 110, 408.
[7] Ceriello A.: “Cardiovascular effects of acute hyperglycaemia: pathophysiological underpinnings”. Diab. Vasc. Dis. Res., 2008, 5, 260.
[8] Ceriello A.: “Acute hyperglycaemia: a ‘new’ risk factor during myocardial infarction”. Eur. Heart J., 2005, 26, 328.
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