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Perivascular epithelioid cell tumor of vulva: a rare case

  • R. Tasaka1
  • Y. Hashiguchi1,*,
  • M. Kasai1
  • T. Fukuda1
  • T. Ichimura1
  • T. Yasui1
  • T. Sumi1

1Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka City, Japan

DOI: 10.12892/ejgo4158.2019 Vol.40,Issue 1,February 2019 pp.148-150

Accepted: 15 March 2017

Published: 10 February 2019

*Corresponding Author(s): Y. Hashiguchi E-mail: hashiguchi@med.osaka-cu.ac.jp

PDF (1.36 MB)

Abstract

Background: Perivascular epithelioid cell tumor (PEComa) is very rare mesenchymal tumor with an unpredictable natural history. To the best of the present authors’ knowledge, there is only one reported case of PEComa of vulva in the English language medical literature. Case Report: A 49-year-old woman presented with PEComa of vulva. The diagnosis was established postoperatively by immunohistochemistry. To date, two months after operation, the patient is alive with no evidence of recurrence or metastasis. Conclusion: A variety of imaging methods and pathological methods including a surgical resection with clear margin may be necessary in cases of patients with mesenchymal tumor of vulva suspecting PEComa. Urgent diagnosis and treatment of these patients seemed to be critical.

Keywords

Perivascular epithelioid cell tumor; PEComa; Vulva

Cite and Share

R. Tasaka,Y. Hashiguchi,M. Kasai,T. Fukuda, T. Ichimura,T. Yasui,T. Sumi. Perivascular epithelioid cell tumor of vulva: a rare case. European Journal of Gynaecological Oncology. 2019. 40(1);148-150.

URL:

https://www.ejgo.net/articles/10.12892/ejgo4158.2019

References

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[3] Henry B.A., Anil V.P.: “Malignant perivascular epithelioid cell tumor (PEComa) of the uterus with late renal and pulmonary metastases: a case report with review of the literature”. Diagnostic Pathol., 2007, 2, 45.

[4] Tazelaar H.D., Batts K.P., Srigley J.R.: “Primary extrapulmonary sugar tumor (PEST): a report of four cases”. Mod. Pathol, 2001, 14, 615.

[5] Bonetti F., Pea M., Martignoni G., Zamboni G.: “PEC and sugar”. Am. J. Surg. Pathol., 1992, 16, 307.

[6] Laura A.G., Sharon L.M., Alan R.S., Kumarasen C.: “Recurrent perivascular epithelioid cell tumor of the uterus (PEComa): an immunohistochemical study and review of the literature”. Gynecol. Oncol., 2003, 90, 677.

[7] Dimmer A., Seitz G., Hohenberger W., Kirchner T., Faller G.: “Late pulmonary metastasis in uterine PEComa’’. J. Clin. Pathol., 2003, 56, 627.

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