Article Menu

Export Article

More by Authors Links

Article Data

  • Views 516
  • Dowloads 113

Case Reports

Open Access

Invasive molar pregnancy mimicking choriocarcinoma. A case

  • C. Sofoudis1,*,
  • A. Tzivelopoulou2
  • D. Fagrezos3
  • C. Anastasiadis2
  • A. Kavatha2
  • E. Papamargaritis1
  • A. Gerolymatos1

1Department of Obstetrics and Gynecology, Konstandopoulio General Hospital, Athens, Greece

2Department of Utrasound Tomography, Konstandopoulio General Hospital, Athens, Greece

3Department of Computed Tomography, Konstandopoulio General Hospital, Athens, Greece

DOI: 10.12892/ejgo4161.2018 Vol.39,Issue 6,December 2018 pp.1012-1014

Published: 15 December 2018

*Corresponding Author(s): C. Sofoudis E-mail: chrisostomos.sofoudis@gmail.com

PDF (248.96 kB)

Abstract

Molar pregnancy, also known as hydatidiform mole, represents a figuration of noncancerous (benign) tumor, originating from uterus. After the fertilization instead of a viable and well-growing pregnancy, there is an increasing and pathologic production of placental cysts. According to the completion of the cysts, molar pregnancy can be divided into a complete and an incomplete (partial) form. Molar pregnancy can be located inside the uterine cavity or can be invasive with malignant complications. A small percentage can be malignant transformed, undergoing gestational trophoblastic neoplasias (GNT). GNT are classified histologically into three distinct subgroubs: choriocarcinoma destruens (invasive mole), choriocarcinoma(CC), and the very rare placental site trophoblastic tumor (PSTT). The authors present a case of a 27 year-old female patient in the 2nd trimester of gestation successfully diagnosed and treated as invasive molar pregnancy.

Keywords

Molar pregnancy; Trophoblastic disease; Choriocarcinoma.

Cite and Share

C. Sofoudis,A. Tzivelopoulou,D. Fagrezos,C. Anastasiadis,A. Kavatha,E. Papamargaritis,A. Gerolymatos. Invasive molar pregnancy mimicking choriocarcinoma. A case. European Journal of Gynaecological Oncology. 2018. 39(6);1012-1014.

URL:

https://www.ejgo.net/articles/10.12892/ejgo4161.2018

References

[1] Berkowitz R.S., Goldstein D.P.: The management of molar pregnancy and gestational trophoblastic tumors”. In: RC Knapp, RS Berkowitz (eds). Gynecologic Oncology. New York: McGraw–Hill, 1993, 328.

[2] Seckl M.J., Fisher R.A., Salerno G., Rees H., Paradinas F.J., Foskett M., Newlands E.S.: “Choriocarcinoma and partial hydatidform moles”. Lancet, 2000, 356, 36.

[3] Hurteau J.A.: “Gestional trophoblastic disease: management of hydatidiform mole”. Clin. Obstet. Gynecol., 2003, 46, 557.

[4] Ngan S., Seckl M.J.: “Gestational trophoblastic neoplasia management: an update”. Curr. Opion. Oncol., 2007, 19, 486.

[5] Hancock B.W., Tidy J.A.: “Current management of molar pregnancy”. J. Reprod. Med., 2002, 47, 347.

[6] Benson C.B., Genest D.R., Bernstein M.R., Soto-Wright V., Goldstein D.P., Berkowitz R.S.: “Sonographic appearance of first trimester complete hydatidiform moles”. J. Ultrasound Obstet. Gynecol., 2000, 16, 188.

[7] Ngan H.Y., Bender H., Benedet J.L., Jones H., Montruccoli G.C,. Pecorelli S., FIGO Committee on Gynecologic Oncology: “Gestational trophoblastic neoplasia, FIGO 2000 staging and classification”. Int. J. Gynaecol. Obstet., 2003, 83, 175.

[8] Zhou Q., Lei X-Y., Xie Q., Gardoza J.D.: “Sonographic and Doppler imaging in the diagnosis and treatment of gestational trophoblastic disease: a 12 year experience”. J. Ultrasound Med., 2005, 24, 15.

[9] Seckl M.J., Sebire N.J., Berkowitz R.S.: “Gestational trophoblastic disease”. Lancet, 2010, 376, 717.

[10] Seckl M.J., Fischer R.A., Salerno G., Rees H., Paradinas F.J., Foskett M., Newlands E.S.: “Choriocarcinoma and partial hyadatidiform moles”. Lancet, 2000, 356, 36.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top