Article Data

  • Views 3269
  • Dowloads 127

Case Reports

Open Access

Invasive molar pregnancy mimicking choriocarcinoma. A case

  • C. Sofoudis1,*,
  • A. Tzivelopoulou2
  • D. Fagrezos3
  • C. Anastasiadis2
  • A. Kavatha2
  • E. Papamargaritis1
  • A. Gerolymatos1

1Department of Obstetrics and Gynecology, Konstandopoulio General Hospital, Athens, Greece

2Department of Utrasound Tomography, Konstandopoulio General Hospital, Athens, Greece

3Department of Computed Tomography, Konstandopoulio General Hospital, Athens, Greece

DOI: 10.12892/ejgo4161.2018 Vol.39,Issue 6,December 2018 pp.1012-1014

Published: 15 December 2018

*Corresponding Author(s): C. Sofoudis E-mail: chrisostomos.sofoudis@gmail.com

PDF (248.96 kB) View Full-text

Abstract

Molar pregnancy, also known as hydatidiform mole, represents a figuration of noncancerous (benign) tumor, originating from uterus. After the fertilization instead of a viable and well-growing pregnancy, there is an increasing and pathologic production of placental cysts. According to the completion of the cysts, molar pregnancy can be divided into a complete and an incomplete (partial) form. Molar pregnancy can be located inside the uterine cavity or can be invasive with malignant complications. A small percentage can be malignant transformed, undergoing gestational trophoblastic neoplasias (GNT). GNT are classified histologically into three distinct subgroubs: choriocarcinoma destruens (invasive mole), choriocarcinoma(CC), and the very rare placental site trophoblastic tumor (PSTT). The authors present a case of a 27 year-old female patient in the 2nd trimester of gestation successfully diagnosed and treated as invasive molar pregnancy.

Keywords

Molar pregnancy; Trophoblastic disease; Choriocarcinoma.

Cite and Share

C. Sofoudis, A. Tzivelopoulou, D. Fagrezos, C. Anastasiadis, A. Kavatha, E. Papamargaritis, A. Gerolymatos. Invasive molar pregnancy mimicking choriocarcinoma. A case. European Journal of Gynaecological Oncology. 2018; 39(6): 1012-1014. doi: 10.12892/ejgo4161.2018

References

[1] Berkowitz R.S., Goldstein D.P.: The management of molar pregnancy and gestational trophoblastic tumors”. In: RC Knapp, RS Berkowitz (eds). Gynecologic Oncology. New York: McGraw–Hill, 1993, 328.

[2] Seckl M.J., Fisher R.A., Salerno G., Rees H., Paradinas F.J., Foskett M., Newlands E.S.: “Choriocarcinoma and partial hydatidform moles”. Lancet, 2000, 356, 36.

[3] Hurteau J.A.: “Gestional trophoblastic disease: management of hydatidiform mole”. Clin. Obstet. Gynecol., 2003, 46, 557.

[4] Ngan S., Seckl M.J.: “Gestational trophoblastic neoplasia management: an update”. Curr. Opion. Oncol., 2007, 19, 486.

[5] Hancock B.W., Tidy J.A.: “Current management of molar pregnancy”. J. Reprod. Med., 2002, 47, 347.

[6] Benson C.B., Genest D.R., Bernstein M.R., Soto-Wright V., Goldstein D.P., Berkowitz R.S.: “Sonographic appearance of first trimester complete hydatidiform moles”. J. Ultrasound Obstet. Gynecol., 2000, 16, 188.

[7] Ngan H.Y., Bender H., Benedet J.L., Jones H., Montruccoli G.C,. Pecorelli S., FIGO Committee on Gynecologic Oncology: “Gestational trophoblastic neoplasia, FIGO 2000 staging and classification”. Int. J. Gynaecol. Obstet., 2003, 83, 175.

[8] Zhou Q., Lei X-Y., Xie Q., Gardoza J.D.: “Sonographic and Doppler imaging in the diagnosis and treatment of gestational trophoblastic disease: a 12 year experience”. J. Ultrasound Med., 2005, 24, 15.

[9] Seckl M.J., Sebire N.J., Berkowitz R.S.: “Gestational trophoblastic disease”. Lancet, 2010, 376, 717.

[10] Seckl M.J., Fischer R.A., Salerno G., Rees H., Paradinas F.J., Foskett M., Newlands E.S.: “Choriocarcinoma and partial hyadatidiform moles”. Lancet, 2000, 356, 36.

Submission Turnaround Time

Top