Oncology cytology and HPV DNA testing in women with cervical ectopy

Objective: To analyse women with ectopy, conventional Pap smear (CPS) and liquid-based cytology (LBC), high-risk HPV (HR-HPV) and its relationship to ectopic size. Materials and Methods: The authors selected 51 women with ectopy, without therapy, negative CPS, and no HPV-induced effect. The authors performed colposcopy, LBC, and HPV testing. They performed computerized planimetry to calculate the percentage of the ectopic area (PEA). The data were analyzed statistically. Results: The mean age was 25.6 years. LBC confirmed CPS predominating metaplastic and/or glandular epithelia, negative deviation to BV, and reactive/inflammatory conclusion. The authors detected atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesions (LSIL) in 17.6% in LBC. HR-HPV was positive in 33% (p = 0.320), with a mean age of 22.8 years and with predominance of HPV other types (OT) in 25.5%. The mean PEA in HPV positive patients was 34.57% (p = 0.664). Conclusion: LBC confirmed the CPS. HPV OT predominated in the age group younger than 25 years. There was no relationship between HR-HPV and ectopic size.

Ectopy; Conventional Pap smear; Liquid- based cytology; HPV-HR

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