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Case Reports

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The longest period to recurrence of granulosa cell ovarian tumor: 41 years after initial diagnosis

  • M. Terzic1,2,3,*,
  • I. Likic Ladjevic4,5
  • N. Ladjevic5,6
  • S. Terzic1
  • J. Dotlic4,5
  • N. Arsenovic7
  • A. S. Laganà8
  • A. Vereczkey9

1Department of Medicine, Nazarbayev University School of Medicine, Astana

2Department of Gynecology, National Research Center of Mother and Child Health, University Medical Center, Astana (Kazakhstan)

3Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburg School of Medicine, Pittsburg, Pennsylvania (USA)

4Clinic of Obstetrics and Gynecology, Clinical Centre of Serbia, Belgrade

5Medical Faculty, University of Belgrade, Belgrade

6Center for Anesthesiology and Resuscitation, Clinical Centre of Serbia, Belgrade (Serbia)

7Department of Cellular Pathology, PathLinks Pathology Services, Lincoln County Hospital, Lincoln (UK)

8Department of Obstetrics and Gynecology “Filippo Del Ponte” Hospital, University of Insubria, Varese (Italy)

9Versys Clinics Budapest Human Reproduction Institute, Budapest (Hungary

DOI: 10.12892/ejgo4470.2018 Vol.39,Issue 5,October 2018 pp.800-802

Published: 10 October 2018

*Corresponding Author(s): M. Terzic E-mail: terzicmilan@yahoo.co.uk

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Abstract

Granulosa cell tumors (GCTs) are characterized by slow growth, local spread, and late recurrence. The authors report the case unique for both unusually large dimensions of the recurring tumor and the fact that it was confined only to the omentum, where it has recurred 41 years after the initial surgery including salpingo-oophorectomy. This is the longest reported period from initial diagnosis to the recurrence of GCT. This case report is important as it proves that recurrence of GCT is possible even after an extremely long period of time after the initial surgery, due to the nature of this tumor, and the inhibition of apoptosis process.

Keywords

Granulosa cell tumor; Ovary; Omentum; Relapse; Apoptosis.

Cite and Share

M. Terzic,I. Likic Ladjevic,N. Ladjevic,S. Terzic,J. Dotlic,N. Arsenovic,A. S. Laganà,A. Vereczkey. The longest period to recurrence of granulosa cell ovarian tumor: 41 years after initial diagnosis. European Journal of Gynaecological Oncology. 2018. 39(5);800-802.

URL:

https://www.ejgo.net/articles/10.12892/ejgo4470.2018

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