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Case Reports

Open Access

Postpartum choriocarcinoma: a rare case report and review of literature

  • Na Guo1,2
  • R. Yin1,2
  • Q. Li1,2
  • L. Song1,2
  • D. Wang1,2,*,

1The Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, Sichuan

2Key laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education ,China

DOI: 10.12892/ejgo4537.2019 Vol.40,Issue 3,June 2019 pp.480-483

Published: 10 June 2019

*Corresponding Author(s): D. Wang E-mail:


Background: Postpartum choriocarcinoma is a rare complication of pregnancy; early diagnosis is important because this rare condition is potentially curable with appropriate chemotherapy. Case Report: Twenty-nine women with postpartum choriocarcinoma were treated at West China Second University Hospital. The most common symptom among the 29 patients with postpartum choriocarcinoma was irregular vaginal bleeding (27/29), one patient had amenorrhea symptoms (1/29), and one patient with ultrasound showed uterine lesion with no symptom (1/29). Diagnosis was made by the level of serum β-hCG, pelvic ultrasound, and radiological investigation. Treatment with multiagent chemotherapy was successful in all cases. Conclusions: The most common symptom of patients with postpartum choriocarcinoma was genital bleeding, and the overall prognosis may be improved by early diagnosis and an appropriate chemotherapy regimen.


Postpartum choriocarcinoma; Early diagnosis; Clinical manifestation; Gestational trophoblast tumor.

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Na Guo,R. Yin,Q. Li,L. Song,D. Wang. Postpartum choriocarcinoma: a rare case report and review of literature. European Journal of Gynaecological Oncology. 2019. 40(3);480-483.


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