Postpartum choriocarcinoma: a rare case report and review of literature

Background: Postpartum choriocarcinoma is a rare complication of pregnancy; early diagnosis is important because this rare condition is potentially curable with appropriate chemotherapy. Case Report: Twenty-nine women with postpartum choriocarcinoma were treated at West China Second University Hospital. The most common symptom among the 29 patients with postpartum choriocarcinoma was irregular vaginal bleeding (27/29), one patient had amenorrhea symptoms (1/29), and one patient with ultrasound showed uterine lesion with no symptom (1/29). Diagnosis was made by the level of serum β-hCG, pelvic ultrasound, and radiological investigation. Treatment with multiagent chemotherapy was successful in all cases. Conclusions: The most common symptom of patients with postpartum choriocarcinoma was genital bleeding, and the overall prognosis may be improved by early diagnosis and an appropriate chemotherapy regimen.

Postpartum choriocarcinoma; Early diagnosis; Clinical manifestation; Gestational trophoblast tumor.

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