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Sister Mary Joseph’s nodules as the presenting symptom of primary peritoneal carcinoma: a case report

  • T. Kihara1,*,
  • T. Kenzaka2
  • C. Suzuki1
  • Y. Nakashima1
  • S. Mochizuki1
  • M. Maruo1

1Department of Obstetrics and Gynecology, Hyogo Prefectural Kaibara Hospital, Tanba

2Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Kobe (Japan)

DOI: 10.12892/ejgo4559.2019 Vol.40,Issue 3,June 2019 pp.508-511

Published: 10 June 2019

*Corresponding Author(s): T. Kihara E-mail: tomosuke_usababy@yahoo.com

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Abstract

Sister Mary Joseph’s nodule as the presenting symptom of primary peritoneal cancer is quite a rare finding. The authors report here an 82-year-old patient with Sister Mary Joseph’s nodule. She was diagnosed with primary peritoneal cancer and treated with surgical excision. Histological examination showed a papillary as well as a tubular pattern in the tumor. Adjuvant chemotherapy was administered but was discontinued because of the occurrence of pancytopenia. Although she could not avail of combination therapy, no recurrence has been observed at until now.

Keywords

Sister Mary Joseph’s nodule; Peritoneal cancer; Surgical excision; Adjuvant chemotherapy.

Cite and Share

T. Kihara, T. Kenzaka, C. Suzuki, Y. Nakashima, S. Mochizuki, M. Maruo. Sister Mary Joseph’s nodules as the presenting symptom of primary peritoneal carcinoma: a case report. European Journal of Gynaecological Oncology. 2019; 40(3): 508-511. doi: 10.12892/ejgo4559.2019

References

[1] Schickler R.L., Abdallah R., McClung E.C., Shahzad M.M.K.: “Primary peritoneal carcinoma presenting as a Sister Mary Joseph’s nodule: A case report and review of the literature”. Gynecol. Oncol. Rep., 2016, 17, 20.

[2] Touraud J.P., Lentz N., Dutronc Y., Mercier E., Sagot P., Lambert D.: “Umbilical cutaneous metastasis (Sister Mary Joseph’s nodule) as the presenting symptom of an ovarian carcinoma”. Gynecol. Obstét. Fertil., 2000, 28, 719.

[3] Al-Mashat F., Sibiany A.M.: “Sister Mary Joseph’s nodule of the umbilicus: Is it always of gastric origin? A review of eight cases at different sites of origin”. Indian J. Cancer, 2010, 47, 65.

[4] Iavazzo C., Madhuri K., Essapen S., Akrivos N., Tailor A., ButlerManuel S.: “Sister Mary Joseph’s Nodule as a First Manifestation of Primary Peritoneal Cancer”. Case Rep. Obstet. Gynecol., 2012, 2012, 467240

[5] Galvañ V.G.: “Sister Mary Joseph’s nodule”. Ann. Intern. Med.,1998, 128, 410.

[6] Beksac K., Irkkan C., Argun G., Cetin B.: “A Serous Peritoneal Cancer Revealing Itself with Double Breast Cancer Metastases in 2 Different Periods”. Appl. Immunohistochem. Mol. Morphol., 2016 Dec 9. [Epub ahead of print]

[7] Zhang C.J., Sun G.P., Liu H., Peng W.R., Xiong F.X., Pan Y.Y., Da J.: “Primary clear cell adenocarcinoma of the peritoneum presents as Sister Mary Joseph’s nodule: a case report and literature review”. Eur. J. Gynaecol. Onco., 2014, 36, 745.

[8] Premkumar M., Rangegowda D., Vyas T., Grover S., Joshi Y.K., Sharma C., Sahney A.: “Cholangiocarcinoma presenting as a Sister Mary Joseph nodule”. AGC Case Rep. J., 2016, 3, 209.

[9] Kawai T., Tominaga S., Hori S., Ogata S. Nakanishi K., Kawahara K., et al.: Peritoneal malignant mesothelial hyperplasia (RMH) of the peritoneum. Immunohistochemical and florescence in situ hybridization (FISH) analyses. J. Clin. Pathol., 2016, 69, 706.

[10] Gabriele R., Conte M., Egidi F., Borghese M.: “Umbilical metastases: current viewpoint. World. J. Surg. Oncol., 2005, 3,13.

[11] Kurt S., Camuzcuoglu H., Camuzcuoglu A., Dicle N.: “Tinar S: Umbilical metastasis of serous component as a first sign mixed type epithelial ovarian cancer”. Eur. J. Gynaecol. Oncol., 2009, 30, 455.

[12] Japan Society of Gynecologic Oncology: “Japanese ovarian cancer treatment guidelines”. Available at: https://jsgo.or.jp/en/index.html


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