Uterine adenosarcoma in a patient following microwave endometrial ablation: a case report

In Japan, almost six million women are said to be suffering from menorrhagia. Microwave endometrial ablation (MEA) is a minimally invasive and effective surgical treatment for dysfunctional uterine bleeding using the application of microwave energy to the en-dometrium. Its popularity has been increasing over time in many countries because of its safety and simplicity. Recently, a number of cases of medical complications after MEA have been reported. Here, the authors present the first reported case of adenosarcoma diag-nosed in a woman, five years after treatment with MEA. This finding highlights the need for gynecologists to use caution and perform close patient follow-up for a prolonged time period after MEA.

MEA; Adenosarcoma

[1] Yeasmin S., Nakayama K., Ishibashi M., Katagiri A., Iida K., Nakayama N., et al.: “Microwave endometrial ablation as an alter-native to hysterectomy for the emergent control of uterine bleeding in patients who are poor surgical candidates”. Arch. Gynecol. Obstet., 2009, 280, 279.

[2] Nakayama K., Rahman M.T., Rahman M., Ishikawa M., Yeasmin S., Katagiri A., et al.: “Microwave endometrial ablation is a highly ef-ficacious way to emergently control life-threatening uterine hemor-rhage”. Arch. Gynecol. Obstet., 2011, 283, 1065.

[3] Nakamura K., Nakayama K., Ishikawa M., Katagiri H., Ishibashi T., Sato E., et al.: “Efficacy of microwave ablation for the treatment of endometrial carcinoma: A report of 3 cases”. Oncol Lett., 2016, 11, 3025.

[4] Yeasmin S., Nakayama K., Ishibashi M., Katagiri A., Iida K., Nakayama N., et al.: “Microwave endometrial ablation as an alter-native to hysterectomy for the emergent control of uterine bleeding in patients who are poor surgical candidates”. Arch. Gynecol. Obstet., 2009, 280, 279.

[5] Sanuki K., Nakayama K., Nakamura K., Ishibashi T., Ishikawa M., Ishikawa N., Kyo S.: “Rapidly enlarged uterus following microwave endometrial ablation: A case report”. Clin. Exp. Obstet. Gynecol., 2017, in press.

[6] Das S., Kirwan J., Drakeley A.J., Kingsland C.R.: “Pelvic abscess following microwave endometrial ablation”. BJOG, 2005, 112, 118.

[7] Sharp H.T.: “Endometrial ablation: postoperative complications”. Am. J. Obstet. Gynecol., 2012, 207, 242.

[8] Nakayama K., Nakamura K., Ishibashi T., Ishikawa M., Kyo S.: “Mi-crowave endometrial ablation at a frequency of 2.45 GHz for men-orrhagia: analysis of its efficacy, recurrence rate, and complications. Clin. Exp. Obstet. Gynecol., 2017, 5, 695.

[9] Shacter E., Weitzman S.A.: “Chronic inflammation and cancer”. On-cology, 2002, 16, 217.