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Serous endometrial intraepithelial carcinoma diagnosed by hysteroscopic transcervical resection

H. Matsubara¹
Y. Hashiguchi^1,*,
M. Kasai¹
T. Fukuda¹
T. Ichimura¹
T. Yasui¹
T. Sumi¹

¹Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka, Japan

DOI: 10.12892/ejgo4645.2019 Vol.40,Issue 5,October 2019 pp.889-891

Accepted: 29 March 2018

Published: 10 October 2019

*Corresponding Author(s): Y. Hashiguchi E-mail: hashiguchi@med.osaka-cu.ac.jp

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Abstract

Background: Serous endometrial intraepithelial carcinoma (SEIC) is very rare, and the diagnosis is made through hysterectomy in most cases. To the best of the present authors’ knowledge, there is only three reported cases of SEIC diagnosed by hysteroscopic transcervical resection in the English language medical literature. Case Report: A 68-year-old woman presented with SEIC. The initial diagnosis was established by hysteroscopic transcervical resection and immunohistochemistry. The final diagnosis was established postoperatively by hysterectomy. To date, five months after operation, the patient is alive with no evidence of recurrence or metastasis. Conclusion: Hysteroscopic exam may be necessary in cases of patients with an abnormal cytology or histology of endometrium to detect SEIC.

Keywords

Serous endometrial intraepithelial carcinoma; Hysteroscopic transcervical resection

Cite and Share

H. Matsubara,Y. Hashiguchi,M. Kasai,T. Fukuda,T. Ichimura,T. Yasui,T. Sumi. Serous endometrial intraepithelial carcinoma diagnosed by hysteroscopic transcervical resection. European Journal of Gynaecological Oncology. 2019. 40(5);889-891.

URL:

https://www.ejgo.net/articles/10.12892/ejgo4645.2019

References

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[2] Pathiraja P., Dhar S., Haldar K.: “Serous endometrial intraepithelial carcinoma: a case series and literature review”. Cancer Manag. Res., 2013, 5, 117.

[3] Kawata M., Miyoshi A., Fujikawa E., Kanao S., Takeda M., Mimura M., Nagamatsu M., Yokoi T..: “Serous Endometrial Intraepithelial Carcinoma: Case Report and Literature Review”. J. Clin. Gynecol. Obstet., 2017, 6, 49.

[4] Ichinose T., Nakagawa S., Namai S., Shiba M., Shimizu M., Kanda R., et al.: “Serous Endometrial Intraepithelial Carcinoma Involving Endometrial Polyp Diagnosed by Transcervical Resection: A Case Report”. J. Clin. Case Rep., 2016, 6, 678.

[5] Yasuda M., Katoh T., Hori S., Suzuki K., Ohno K., Maruyama M., et al.: “Endometrial intraepithelial carcinoma in association with polyp: review of eight cases”. Diagn. Pathol., 2013, 8, 25.

[6] Kaku S., Moriya T., Ushioda N., Nakai Y., Shimoya K., Nakamura T.: “Acase of serous endometrial intraepithelial carcinoma with p53 positivity for six years”. J. Obstet. Gynaecol. Res., 2012, 38, 455.

[7] Ono K., Hayashi H., Tateno M., Tanaka R., Suzuki R., Maruyama Y., et al.: “Uterine superficial serous carcinomas and extensive serous endometrial intraepithelial carcinomas: clinicopathological analysis of 6 patients”. Int. J. Clin. Exp. Pathol., 2014, 7, 7979.

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