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Case Reports

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Primary endometrial and cervical squamous cell carcinoma in situ, a rare coexistence: case report and literature review

  • Ercan Yilmaz1,*,
  • Saadet Alan2
  • Simge Faydali1
  • Rauf Melekoglu1
  • Hasan Gokce2
  • Hasim Kural1'1

1Inonu University Turgut Ozal Medical Centre Obstetrics and Gynecology Department, Malatya (Turkey)

2Inonu University Turgut Ozal Medical Centre Pathology Department, Malatya (Turkey)

DOI: 10.12892/ejgo4647.2019 Vol.40,Issue 6,December 2019 pp.1073-1075

Published: 10 December 2019

*Corresponding Author(s): Ercan Yilmaz E-mail: ercanyilmazgyn@yahoo.com

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Abstract

Although the most common gynecologic tumor of the female genital system is endometrial adenocarcinoma, endometrial squamous cell carcinoma (ESCC) is rarely seen. The presence of ESCC is commonly known as a concomitant tumor secondary to cervical squa-mous cell carcinoma (SCC). However primary endometrial squamous cell carcinoma (PESCC) is a more rare tumor type. In situ carci-noma, defined as the inflammation of entire intraepithelial tissue with dysplastic cells without identifying any concomitant invasion or metastasis, is considered to be among the precancerous lesions of the female genital system. In situ squamous cell carcinoma cases, es-pecially identified in the cervical region, can be rarely observed in the endometrial tissue. In this case report, the authors aimed to discuss a case of cervical and ESCC in situ which is reported for the first time in the literature.

Keywords

In situ carcinoma; Squamous cell carcinoma; Primary endometrial squamous cell carcinoma.

Cite and Share

Ercan Yilmaz, Saadet Alan, Simge Faydali, Rauf Melekoglu, Hasan Gokce, Hasim Kural1'. Primary endometrial and cervical squamous cell carcinoma in situ, a rare coexistence: case report and literature review. European Journal of Gynaecological Oncology. 2019; 40(6): 1073-1075. doi: 10.12892/ejgo4647.2019

URL:

https://www.ejgo.net/articles/10.12892/ejgo4647.2019

References

[1] Yilmaz E., Celik O., Celik E., Turkcuoglu I., Simsek Y., Karaer A., et al.: “XPD and XRCC1 gene polymorphism in patient with normal and abnormal cervical cytology by pap smear“. Eur. Rev. Med. Phar-macol. Sci., 2012, 16, 1713.

Zidi Y.S.H., Bouraoui K., Atallah N., Kchir N., Haouet S.: “Primary in situ squamous cell carcinoma of the endometrium, with extensive squamous metaplasia and dysplasia“. Gyncol. Oncol., 2003, 88, 444.

[3] Jetley S., Jairajpuri ZA., Hassan MJ., Madaan G., Jain R.: “Primary endometrial squamous cell carcinoma in situ: Report a rare disease”. Sultan. Qaboos. Univ. Med.J., 2015, 15, 559.

[4] Fluhmann C.F.: “The histogenesis of squamous cell metaplasia of the cervix and endometrium“. Surg. Gynecol. Obstet., 1953, 97, 45.


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