Small cell ovarian carcinoma hypercalcemic type and endometrial adenocarcinoma in a 49-year-old patient: a very rare case

Background: Small cell ovarian carcinoma hypercalcemic type (SCCOHT) is a rare ovarian malignancy with less than 400 cases worldwide. However, it affects mainly young women and has poor prognosis. The incidence of concurrent endometrial and ovarian cancer is as low as 10%, and has not been described, to our knowledge, with SCCOHT. Case Report: This is a rare case of a 49-year-old female who presented with abdominal pain, constipation, asymptomatic hypercalcemia, a large palpable abdominal mass, and was diagnosed with SCCOHT with concurrent Grade I endometrial adenocarcinoma endometroid type. Conclusion: This is an interesting case due to the concurrent endometrial cancer, the size of the tumor, and the age of the patient and aims to increase clinical suspicion around SCCOHT. The importance of the MDT should be highlighted, especially for this type of tumors which can be a diagnostic and treatment challenge.

Ovarian cancer; Small cell ovarian carcinoma; Endometrial cancer.

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