Article Data

  • Views 2055
  • Dowloads 146

Case Reports

Open Access

Primary management of an extremely large, invasive mucinous ovarian adenocarcinoma: a case report

  • L. N. Abaid1
  • N. Zekry2
  • TANJA GORANOVI?3
  • R. C. Kankus1
  • B. H. Goldstein1,*,

1Gynecologic Oncology Associates, Hoag Cancer Center, Newport Beach, CA (USA)

2Department of Pathology, Hoag Memorial Hospital Presbyterian, Newport Beach, CA (USA)

3Memorial Care Imaging Center at Orange Coast, Fountain Valley, CA (USA)

DOI: 10.12892/ejgo5018.2019 Vol.40,Issue 6,December 2019 pp.1044-1046

Published: 10 December 2019

*Corresponding Author(s): B. H. Goldstein E-mail: bram@gynoncology.com

Abstract

Background: Mucinous tumors are typically benign lesions, although they can be aggressive and exhibit stromal invasion. Moreover, studies have reported on extremely large mucinous ovarian malignancies that have infiltrated the abdomen and pelvis. Case Report: The authors describe the history of a 52-year-old woman who presented with a 40-cm mucinous ovarian neoplasm that weighed nearly 22 kg. Initially, confirming the diagnosis was complicated and thus, immunohistochemistry (e.g., pancytokeratin, p53, PAX 8, and CK7) staining was indicated. Conclusion: Mucinous ovarian tumors are often associated with a favorable prognosis, but when they are ex-tremely large, disease management can be relatively precarious because of the potential for cardiovascular and intraoperative compli-cations. Since there is some difficulty in assessing large mucinous tumors, immunohistochemistry staining and judicious clinical judgment are essential.

Keywords

Mucinous ovarian tumors; Large abdominal mass; Patient management; Case report.

Cite and Share

L. N. Abaid,N. Zekry,TANJA GORANOVI?,R. C. Kankus,B. H. Goldstein. Primary management of an extremely large, invasive mucinous ovarian adenocarcinoma: a case report. European Journal of Gynaecological Oncology. 2019. 40(6);1044-1046.

References

[1] Jagtap S.V., Dhawan S.D., Jagtap S.S., Kshirsagar N.S.: “Mucinous cystadenocarcinoma of the ovary presenting as a giant pelvic-ab-dominal mass”. Int. J. Med. Sci. Public Health, 2014, 3, 1305.

[2] Nakamura M., Saitoh M., Miyamoto S., Kubo Y., Tomita H., Andoh A.: “Case of a giant mucinous ovarian carcinoma with bone metas-tasis”. J. Obstet. Gynaecol. Res., 2005, 31, 576.

[3] Brown J., Frumovitz M.: “Mucinous tumors of the ovary: current thoughts on diagnosis and management”. Curr. Oncol. Rep., 2014, 16, 389.

[4] Seidman J.D., Kurman R.J., Ronnett B.M.: “Primary and metastatic mucinous adenocarcinomas in the ovaries: incidence in routine prac-tice with a new approach to improve intraoperative diagnosis”. Am. J. Surg. Pathol., 2003, 27, 985.

[5] Rouzbahman M., Chetty R.: “Republished: mucinous tumours of ap-pendix and ovary: an overview and evaluation of current practice”. Postgrad. Med. J., 2015, 91, 41.

[6] Katke R.D.: “Giant mucinous cystadenocarcinoma of ovary: A case report and review of literature”. J. Midlife Health, 2016, 7, 41.

[7] Forster A., Samaras N., Graf C., Tille J.C., Samaras D.: “Giant mu-cinous ovarian tumor”. Am. J. Med. Sci., 2013, 345, 400.

[8] Kim Y.T., Kim J.W., Choe B.H.: “A case of huge ovarian cyst of 21-year-old young woman”. J. Obstet. Gynaecol. Res., 1999, 25, 275.

[9] Heintz A.P., Odicino F., Maisonneuve P., Quinn M.A.., Benedet J.L., Creasman W.T., et al.: “Carcinoma of the ovary. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer”. Int. J. Gynaecol. Obstet., 2006, 95, S161.

[10] Lee K.R., Young R.H.: “The distinction between primary and metastatic mucinous carcinomas of the ovary: gross and histologic findings in 50 cases”. Am. J. Surg. Pathol., 2003, 27, 281.

[11] Guerrieri C., Högberg T., Wingren S., Fristedt S., Simonsen E., Boeryd B.: “Mucinous borderline and malignant tumors of the ovary. A clinicopathologic and DNA ploidy study of 92 cases”. Cancer, 1994, 74, 2329.

[12] Simons M., Ezendam N., Bulten J., Nagtegaal I., Massuger L.: “Sur-vival of Patients With Mucinous Ovarian Carcinoma and Ovarian Metastases: A Population-Based Cancer Registry Study”. Int. J. Gy-necol. Cancer, 2015, 25, 1208.

[13] Boger-Megiddo I., Weiss N.S.: “Histologic subtypes and laterality of primary epithelial ovarian tumors”. Gynecol. Oncol., 2005, 97, 80.

[14] De Decker K., Speth S., Ter Brugge H.G., Bart J., Massuger L.F.A.G., Kleppe M., et al.: “Staging procedures in patients with mu-cinous borderline tumors of the ovary do not reveal peritoneal or omental disease”. Gynecol. Oncol., 2017, 144, 285.

[15] Jung E.S., Bae J.H., Lee A., Choi Y.J., Park J.S., Lee K.Y.: “Mucinous adenocarcinoma involving the ovary: comparative evaluation of the classification algorithms using tumor size and laterality”. J. Korean Med. Sci., 2010, 25, 220.

[16] Frumovitz M., Schmeler K.M., Malpica A., Sood A.K., Gershenson D. M.: “Unmasking the complexities of mucinous ovarian carci-noma”. Gynecol. Oncol., 2010, 117, 491.

Abstracted / indexed in

Web of Science (WOS) (On Hold)

Journal Citation Reports/Science Edition

Google Scholar

JournalSeek

Submission Turnaround Time

Top