Article Data

  • Views 691
  • Dowloads 140

Case Reports

Open Access

Primary management of an extremely large, invasive mucinous ovarian adenocarcinoma: a case report

  • L. N. Abaid1
  • N. Zekry2
  • TANJA GORANOVI?3
  • R. C. Kankus1
  • B. H. Goldstein1,*,

1Gynecologic Oncology Associates, Hoag Cancer Center, Newport Beach, CA (USA)

2Department of Pathology, Hoag Memorial Hospital Presbyterian, Newport Beach, CA (USA)

3Memorial Care Imaging Center at Orange Coast, Fountain Valley, CA (USA)

DOI: 10.12892/ejgo5018.2019 Vol.40,Issue 6,December 2019 pp.1044-1046

Published: 10 December 2019

*Corresponding Author(s): B. H. Goldstein E-mail: bram@gynoncology.com

Abstract

Background: Mucinous tumors are typically benign lesions, although they can be aggressive and exhibit stromal invasion. Moreover, studies have reported on extremely large mucinous ovarian malignancies that have infiltrated the abdomen and pelvis. Case Report: The authors describe the history of a 52-year-old woman who presented with a 40-cm mucinous ovarian neoplasm that weighed nearly 22 kg. Initially, confirming the diagnosis was complicated and thus, immunohistochemistry (e.g., pancytokeratin, p53, PAX 8, and CK7) staining was indicated. Conclusion: Mucinous ovarian tumors are often associated with a favorable prognosis, but when they are ex-tremely large, disease management can be relatively precarious because of the potential for cardiovascular and intraoperative compli-cations. Since there is some difficulty in assessing large mucinous tumors, immunohistochemistry staining and judicious clinical judgment are essential.

Keywords

Mucinous ovarian tumors; Large abdominal mass; Patient management; Case report.

Cite and Share

L. N. Abaid,N. Zekry,TANJA GORANOVI?,R. C. Kankus,B. H. Goldstein. Primary management of an extremely large, invasive mucinous ovarian adenocarcinoma: a case report. European Journal of Gynaecological Oncology. 2019. 40(6);1044-1046.

References

[1] Jagtap S.V., Dhawan S.D., Jagtap S.S., Kshirsagar N.S.: “Mucinous cystadenocarcinoma of the ovary presenting as a giant pelvic-ab-dominal mass”. Int. J. Med. Sci. Public Health, 2014, 3, 1305.

[2] Nakamura M., Saitoh M., Miyamoto S., Kubo Y., Tomita H., Andoh A.: “Case of a giant mucinous ovarian carcinoma with bone metas-tasis”. J. Obstet. Gynaecol. Res., 2005, 31, 576.

[3] Brown J., Frumovitz M.: “Mucinous tumors of the ovary: current thoughts on diagnosis and management”. Curr. Oncol. Rep., 2014, 16, 389.

[4] Seidman J.D., Kurman R.J., Ronnett B.M.: “Primary and metastatic mucinous adenocarcinomas in the ovaries: incidence in routine prac-tice with a new approach to improve intraoperative diagnosis”. Am. J. Surg. Pathol., 2003, 27, 985.

[5] Rouzbahman M., Chetty R.: “Republished: mucinous tumours of ap-pendix and ovary: an overview and evaluation of current practice”. Postgrad. Med. J., 2015, 91, 41.

[6] Katke R.D.: “Giant mucinous cystadenocarcinoma of ovary: A case report and review of literature”. J. Midlife Health, 2016, 7, 41.

[7] Forster A., Samaras N., Graf C., Tille J.C., Samaras D.: “Giant mu-cinous ovarian tumor”. Am. J. Med. Sci., 2013, 345, 400.

[8] Kim Y.T., Kim J.W., Choe B.H.: “A case of huge ovarian cyst of 21-year-old young woman”. J. Obstet. Gynaecol. Res., 1999, 25, 275.

[9] Heintz A.P., Odicino F., Maisonneuve P., Quinn M.A.., Benedet J.L., Creasman W.T., et al.: “Carcinoma of the ovary. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer”. Int. J. Gynaecol. Obstet., 2006, 95, S161.

[10] Lee K.R., Young R.H.: “The distinction between primary and metastatic mucinous carcinomas of the ovary: gross and histologic findings in 50 cases”. Am. J. Surg. Pathol., 2003, 27, 281.

[11] Guerrieri C., Högberg T., Wingren S., Fristedt S., Simonsen E., Boeryd B.: “Mucinous borderline and malignant tumors of the ovary. A clinicopathologic and DNA ploidy study of 92 cases”. Cancer, 1994, 74, 2329.

[12] Simons M., Ezendam N., Bulten J., Nagtegaal I., Massuger L.: “Sur-vival of Patients With Mucinous Ovarian Carcinoma and Ovarian Metastases: A Population-Based Cancer Registry Study”. Int. J. Gy-necol. Cancer, 2015, 25, 1208.

[13] Boger-Megiddo I., Weiss N.S.: “Histologic subtypes and laterality of primary epithelial ovarian tumors”. Gynecol. Oncol., 2005, 97, 80.

[14] De Decker K., Speth S., Ter Brugge H.G., Bart J., Massuger L.F.A.G., Kleppe M., et al.: “Staging procedures in patients with mu-cinous borderline tumors of the ovary do not reveal peritoneal or omental disease”. Gynecol. Oncol., 2017, 144, 285.

[15] Jung E.S., Bae J.H., Lee A., Choi Y.J., Park J.S., Lee K.Y.: “Mucinous adenocarcinoma involving the ovary: comparative evaluation of the classification algorithms using tumor size and laterality”. J. Korean Med. Sci., 2010, 25, 220.

[16] Frumovitz M., Schmeler K.M., Malpica A., Sood A.K., Gershenson D. M.: “Unmasking the complexities of mucinous ovarian carci-noma”. Gynecol. Oncol., 2010, 117, 491.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top