Article Data

  • Views 205
  • Dowloads 127

Case Reports

Open Access

Uterine lipoleiomyoma misdiagnosed as uterine fibroid in a pregnant woman: a case report and literature review

  • Yunyun Wang1
  • Liping Li1
  • Wei Fan1
  • Rongfang Zheng1
  • Xuefen Fan1
  • Yuzhen Guo1,*,

1Department of Gynecology, The Second Hospital of Lanzhou University, 730000 Lanzhou, Gansu, China

DOI: 10.22514/ejgo.2022.063 Vol.43,Issue 6,December 2022 pp.104-108

Submitted: 17 May 2022 Accepted: 17 June 2022

Published: 15 December 2022

*Corresponding Author(s): Yuzhen Guo E-mail: guoyz@lzu.edu.cn

Abstract

Uterine lipoleiomyoma is a rare variant of leiomyomas, especially in pregnant women. Currently, there is only one case reported in literature, suggesting that without proper knowledge about this disease, there is a high risk that uterine lipoleiomyoma could be misdiagnosed as other gynecological diseases, particularly during pregnancy. Here, we report the case of a 38-year-old female admitted to our department due to intermittent lower abdominal pain and a small amount of vaginal bleeding after menopause. Based on her clinical manifestations, laboratory tests and imaging examinations, she was preoperatively diagnosed as pregnant with uterine fibroid fatty degeneration. Following an induced abortion, she underwent a laparoscopic myomectomy and was diagnosed with uterine lipoleiomyoma on postoperative immunohistochemistry. During a 6-month follow-up, no abnormalities were detected. The obstetric outcomes, diagnosis and treatments of pregnancy with uterine lipoleiomyoma may resemble those of pregnancy with uterine fibroid. Although comprehensive imaging examinations are helpful for preoperative diagnosis, the final diagnosis still relies on postoperative pathological examination.


Keywords

Misdiagnosis; Pregnancy; Uterine fibroid; Uterine lipoleiomyoma


Cite and Share

Yunyun Wang,Liping Li,Wei Fan,Rongfang Zheng,Xuefen Fan,Yuzhen Guo. Uterine lipoleiomyoma misdiagnosed as uterine fibroid in a pregnant woman: a case report and literature review. European Journal of Gynaecological Oncology. 2022. 43(6);104-108.

References

[1] Ghosh B, McKeown B, Gumma A. Lipoleiomyoma. BMJ Case Reports 2011; 2011: bcr0820114577.

[2] Wilke S, Benson J, Roller L. Uterine lipoleiomyoma: case report and review of the literature. Radiology Case Reports. 2022; 17: 954–958.

[3] Nazir HM, Mehta S, Seena CR, Kulasekaran N. Uterine lipoleiomyoma: a report of two cases. Journal of Clinical Imaging Science 2017; 7: 26.

[4] Manila K, Laxmi M, Ranjana P. Cervical myolipoma with pregnancy: report of a case and brief review of literature. Nepal Journal of Obstetrics and Gynaecology. 2009; 4: 54–55.

[5] Yuan Y, Chen L, Zhao T, Yu M. Pathogenesis, diagnosis and treatment of uterine lipoleiomyoma: a review. Biomedicine & Pharmacotherapy. 2021; 142: 112013.

[6] Mulita F, Liolis E, Kehagias D. An enormous pelvic tumor in a 46-year-old woman with an elevated serum CA 125 level, what lies beneath it?Investigation of uterine tumors in postmenopausal women. Menopause Review. 2021; 20: 154–157.

[7] Tyagi N, Tyagi R, Griffin Y. Uterine lipoleiomyoma. BMJ Case Reports. 2014; 2014: bcr2014207763.

[8] Johari B, Koshy M, Sidek S, Hanafiah M. Lipoleiomyoma: a rare benign tumour of the uterus. BMJ Case Reports. 2014; 2014: bcr2014205814.

[9] Chu CY, Tang YK, Chan TS, Wan YH, Fung KH. Diagnostic challenge of lipomatous uterine tumors in three patients. World Journal of Radiology. 2012; 4: 58–62.

[10] Akbulut M, Gündoğan M, Yörükoğlu A. Clinical and pathological features of lipoleiomyoma of the uterine corpus: a review of 76 cases. Balkan Medical Journal. 2014; 31: 224–229.

[11] Mulita F, Iliopoulos F, Plachouri K, Kehagias I. Uterine leiomyoblastoma. BMJ Case Reports. 2021; 14: e241533.

Saleh HS, Mowafy HE, Hameid AAAE, Sherif HE, Mahfouz EM. Does uterine fibroid adversely affect obstetric outcome of pregnancy? BioMed Research International. 2018; 2018: 1–5.

Valenti G, Milone P, D’Amico S, Caldaci LMG, Vitagliano A, Sapia F, et al. Use of pre-operative imaging for symptomatic uterine myomas during pregnancy: a case report and a systematic literature review. Archives of Gynecology and Obstetrics. 2019; 299: 13–33.

[14] Zaima A, Ash A. Fibroid in pregnancy: characteristics, complications, and management. Postgraduate Medical Journal. 2011; 87: 819–828.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top