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A case report of vulvar embryonal rhabdomyosarcoma in an adult pregnant woman

  • Jie Wang1
  • Xuejin Ma1
  • Lin Jiang1
  • Huangfei Yu2
  • Tingchao Li3
  • Ling Wei1
  • Shiguang Li1,*,

1Department of Radiology, the Third Affiliated Hospital of Zunyi Medical University (the First People’s Hospital of ZunYi), 563000 Zunyi, Guizhou, China

2Department of Oncology, the Third Affiliated Hospital of Zunyi Medical University (the First People’s Hospital of ZunYi), 563000 Zunyi, Guizhou, China

3Department of Pathology, the Third Affiliated Hospital of Zunyi Medical University (the First People’s Hospital of ZunYi), 563000 Zunyi, Guizhou, China

DOI: 10.22514/ejgo.2023.046 Vol.44,Issue 3,June 2023 pp.106-109

Submitted: 22 June 2022 Accepted: 13 September 2022

Published: 15 June 2023

*Corresponding Author(s): Shiguang Li E-mail: imaging_sgli@163.com

PDF (6.67 MB) Supplementary material View Full-text

Abstract

Embryonal rhabdomyosarcoma (ERMS) is the most common soft tissue sarcoma in children, but it is rare in adults, where cases are reported as individual cases or series. We present an ERMS found in the vulva of a 24-year-old pregnant woman who complained of a painless soft tissue mass in her left vulva. The mass grew rapidly within a month, and abortion, internal iliac artery embolization, and chemotherapy were performed. Despite an initially good response, cancer unfortunately progressed, and the patient passed away within one year after diagnosis. Adults with ERMSs tend to have poorer outcomes than children, and our case suggests that in some cases, pregnancy may accelerate the deterioration of the tumor.


Keywords

Adult; Embryonal rhabdomyosarcoma; Magnetic resonance imaging; Pregnancy; Vulvar mass


Cite and Share

Jie Wang,Xuejin Ma,Lin Jiang,Huangfei Yu,Tingchao Li,Ling Wei,Shiguang Li. A case report of vulvar embryonal rhabdomyosarcoma in an adult pregnant woman. European Journal of Gynaecological Oncology. 2023. 44(3);106-109.

URL:

https://www.ejgo.net/articles/10.22514/ejgo.2023.046

References

[1] Bompas E, Campion L, Italiano A, Le Cesne A, Chevreau C, Isambert N, et al. Outcome of 449 adult patients with rhabdomyosarcoma: an observational ambispective nationwide study. Cancer Medicine. 2018; 7: 4023–4035.

[2] Panda SP, Chinnaswamy G, Vora T, Prasad M, Bansal D, Kapoor G, et al. Diagnosis and management of rhabdomyosarcoma in children and adolescents: ICMR consensus document. Indian Journal of Pediatrics. 2017; 84: 393–402.

[3] Ruiz-Mesa C, Goldberg JM, Coronado Munoz AJ, Dumont SN, Trent JC. Rhabdomyosarcoma in adults: new perspectives on therapy. Current Treatment Options in Oncology. 2015; 16: 27.

[4] J Jawad N, McHugh K. The clinical and radiologic features of paediatric rhabdomyosarcoma. Pediatric Radiology. 2019; 49: 1516–1523.

[5] He W, Jin Y, Zhou X, Zhou K, Zhu R. Alveolar rhabdomyosarcoma of the vulva in an adult: a case report and literature review. The Journal of International Medical Research. 2020; 48: 300060520905438.

[6] OBER WB, PALMER RE, GLASSY FJ. Rhabdomyosarcoma of the vulva and vagina. AMA Archives of Pathology. 1953; 56: 364–373.

[7] Meseci E, Onculoglu C, Ince U, Teomete M, Eser SK, Demirkıran F. Embryonal rhabdomyosarcoma of the uterine cervix in a pregnant woman. Taiwanese Journal of Obstetrics & Gynecology. 2014; 53: 423–425.

[8] Meazza C, Casanova M, Zaffignani E, Clerici CA, Favini F, Vasquez R, et al. An adolescent with rhabdomyosarcoma during pregnancy. Tumori. 2008; 94: 431–433.

[9] Matsuo K, Eno ML, Im DD, Rosenshein NB. Pregnancy and genital sarcoma: a systematic review of the literature. American Journal of Perinatology. 2009; 26: 507–518.

[10] Akhavan S, Agah J, Nili F. Congenital lymphangioma circumscriptum of vulva presenting as multiple giant mass lesions: a case report and literature review. The Journal of Obstetrics and Gynaecology Research. 2018; 44: 978–982.

[11] Xu H, Sun P, Xu R, Wang L, Shi Y. Aggressive angiomyxoma in pregnancy: a case report and literature review. The Journal of International Medical Research. 2020; 48: 300060520936414.

[12] Little DJ, Ballo MT, Zagars GK, Pisters PW, Patel SR, El-Naggar AK, et al. Adult rhabdomyosarcoma: outcome following multimodality treatment. Cancer. 2002; 95: 377–388.

[13] Ferguson SE, Gerald W, Barakat RR, Chi DS, Soslow RA. Clinicopatho-logic features of rhabdomyosarcoma of gynecologic origin in adults. The American Journal of Surgical Pathology. 2007; 31: 382–389.


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