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Original Research

Open Access

A comparative study on myomectomy and total hysterectomy in the treatment of perimenopausal uterine fibroids

  • Jing Zeng1
  • Jing Wang1
  • Min Wang1
  • Xiaoli Wang1,*,

1Department of Gynecology and Obstetrics, Chengdu Second People’s Hospital, 610017 Chengdu, Sichuan, China

DOI: 10.22514/ejgo.2024.036 Vol.45,Issue 2,April 2024 pp.141-146

Submitted: 21 December 2023 Accepted: 21 January 2024

Published: 15 April 2024

*Corresponding Author(s): Xiaoli Wang E-mail: wangxiaoli3122101@163.com

Abstract

This study aims to compare the clinical efficacy of myomectomy and total hysterectomy in the treatment of perimenopausal uterine fibroids. 124 cases of uterine fibroids were randomly divided into a control group and a study group, each with 62 cases. The control group underwent a total hysterectomy. Study participants underwent a myomectomy. Both groups of patients were observed and compared for surgery-related indicators, quality of life scores, perimenopausal syndrome and inflammatory factors. The study group had a shorter operation time and less intraoperative blood loss (p < 0.05). Before operation, there was no significant difference in Quality of life Short Form 36 (SF-36) score, Interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and IL-10 between both groups (p > 0.05) at 6 months after operation, SF-36 score in both groups were higher than before operation, and IL-6, TNF-α and IL-10 in both groups were higher than before operation (p < 0.05). Perimenopausal syndrome incidence was significantly lower in the study group than in the control group (p < 0.05). Myomectomy is more suitable for treating perimenopausal uterine fibroids.


Keywords

Myomectomy; Total hysterectomy; Perimenopausal period; Uterine fibroids


Cite and Share

Jing Zeng,Jing Wang,Min Wang,Xiaoli Wang. A comparative study on myomectomy and total hysterectomy in the treatment of perimenopausal uterine fibroids. European Journal of Gynaecological Oncology. 2024. 45(2);141-146.

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