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Original Research

Open Access

High-dose-rate intracavitary brachytherapy for non-palpable and non-visible recurrent vaginal stump tumors after hysterectomy

  • M. Sakaguchi1,*,
  • T. Maebayashi1
  • T. Aizawa1
  • N. Ishibashi1
  • T. Saito2

1Department of Radiology, Nihon University School of Medicine, Itabashi-ku, Tokyo

2Sonodakai Radiation Oncology Clinic, Adachi-ku, Tokyo (Japan)

DOI: 10.31083/j.ejgo.2020.01.4758 Vol.41,Issue 1,February 2020 pp.54-59

Published: 15 February 2020

*Corresponding Author(s): M. Sakaguchi E-mail:


Purpose: The purpose of this study was to evaluate patients who were treated with high-dose-rate (HDR) intracavitary brachytherapy for non-palpable and non-visible recurrent vaginal stump that occurred after hysterectomy. Materials and Methods: This retrospective study included 11 patients aged 52–81 (median, 61) years. The HDR brachytherapy was performed using a remote after-loading system (RALS). The dose per fraction was planned at mainly 4 Gy/fraction, twice per week, for a total of 32 Gy. Results: CR and PR were diagnosed on cytology or visual examination in nine (82%) patients and in one (9%) patient, respectively. SD was noted in one (9%) patient. Isolated stump recurrence developed in five patients and the three-year LC rate was 53%. There was no severe acute and late toxicity. Conclusion: Local salvage is possible with a three-year LC rate of 53% with regard to non-palpable and non-visible limited vaginal recurrence of gynecological cancer that responds to HDR brachytherapy (4 Gy/fraction, total 32 Gy).


High-dose-rate intracavitary brachytherapy; Recurrent vaginal stump; Hysterectomy; Remote after-loading system; Gynecological cancer.

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M. Sakaguchi,T. Maebayashi,T. Aizawa,N. Ishibashi,T. Saito. High-dose-rate intracavitary brachytherapy for non-palpable and non-visible recurrent vaginal stump tumors after hysterectomy. European Journal of Gynaecological Oncology. 2020. 41(1);54-59.


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