Article Data

  • Views 560
  • Dowloads 127

Case Reports

Open Access

Two cases of uterus-conserving treatment for early stage endometrial cancer

  • Y.-S. Kwon1
  • K. S. Im2,*,
  • S. B. Yoo2
  • W. I. Kim2

1Department of Obstetrics and Gynecology, Nowon Eulji Medical Center, Eulji University, Seoul

2Department of Anesthesiology and Pain Medicine, Uijeongbu St Mary’s Hospital, College of Medicine, Catholic University of Korea, Seoul (Korea)

DOI: 10.31083/j.ejgo.2020.01.4863 Vol.41,Issue 1,February 2020 pp.145-147

Published: 15 February 2020

*Corresponding Author(s): K. S. Im E-mail: idonga@catholic.ac.kr

Abstract

The aim of study is to present two successful cases of conservative surgical treatment of women with early-stage endometrial cancer who desired to have fertility in the two cases. A 32-year-old nulligravid woman had Stage IA endometrial cancer which was a 1.5-cm sized lesion confined to the left fundal side of the uterus. The other 35-year-old nulligravid woman had a 2-cm sized lesion suspicious for deep myometrial involvement suggesting Stage IB endometrial cancer. The women underwent hysteroscopic complete resection of tumor with safe resection margin just after laparoscopic tubal ligation, followed by insertion of a progesterone-releasing intrauterine device. The patients have no evidence of recurrence for 26 months and 27 months of follow-up, respectively. Hysteroscopic complete resection of tumor with safe margin combined with bilateral tubal ligation, followed by a progesterone-releasing intrauterine device could be a good option for early-stage endometrial cancer.

Keywords

Endometrial cancer; Hysteroscopy; Laparoscopy; Tubal ligation.

Cite and Share

Y.-S. Kwon,K. S. Im,S. B. Yoo,W. I. Kim. Two cases of uterus-conserving treatment for early stage endometrial cancer. European Journal of Gynaecological Oncology. 2020. 41(1);145-147.

References

[1] Baker J., Obermair A., Gebski V., Janda M.: “Efficacy of oral or intrauterine device-delivered progestin in patients with complex endometrial hyperplasia with atypia or early endometrial adenocarcinoma: a meta-analysis and systematic review of the literature”. Gynecol. Oncol., 2012, 125, 263.

[2] Gadducci A., Spirito N., Baroni E., Tana R., Genazzani A.R.: “The fertility-sparing treatment in patients with endometrial atypical hyperplasia and early endometrial cancer: a debated therapeutic option”. Gynecol. Endocrinol., 2009, 25, 683.

[3] Polyzos N.P., Mauri D., Tsioras S., Messini C..I, Valachis A., Messinis I.E.: “Intraperitoneal dissemination of endometrial cancer cells after hysteroscopy: a systematic review and meta-analysis”. Int. J. Gynecol. Cancer., 2010, 20, 261.

[4] Gallos I.D., Yap J., Rajkhowa M., Luesley D.M., Coomarasamy A., Gupta J.K.: “Regression, relapse, and live birth rates with fertilitysparing therapy for endometrial cancer and atypical complex endometrial hyperplasia: a systematic review and metaanalysis”. Am. J. Obstet. Gynecol., 2012, 207, 266.

[5] Gracia C.R., Sammel M.D., Freeman E., Prewitt M., Carlson C., Ray A., et al.: “Impact of cancer therapies on ovarian reserve”. Fertil. Steril., 2012, 97, 134.

[6] Laurelli G., Di Vagno G., Scaffa C., Losito S., Del Giudice M., Greggi S.: “Conservative treatment of early endometrial cancer: preliminary results of a pilot study”. Gynecol. Oncol., 2011, 120, 43.

[7] Mazzon I., Corrado G., Masciullo V., Morricone D., Ferrandina G., Scambia G.: “Conservative surgical management of stage IA endometrial carcinoma for fertility preservation”. Fertil. Steril., 2010, 93, 1286.

[8] Gallos I.D., Krishan P., Shehmar M., Ganesan R., Gupta J.K.: “LNGIUS versus oral progestogen treatment for endometrial hyperplasia: a long-term comparative cohort study”. Hum. Reprod., 2013, 28, 2966.

[9] Orbo A., Vereide A., Arnes M., Pettersen I., Straume B.: “Levonorgestrel-impregnated intrauterine device as treatment for endometrial hyperplasia: a national multicentre randomised trial”. BJOG, 2014, 121, 477.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top