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Original Research

Open Access

Development of high-risk HPV associated cervical dysplasia despite HPV-vaccination: a regional dysplasia center cohort study

  • A.K. Fischer1
  • K. Reuter-Jessen2
  • H.-U. Schildhaus2
  • T. Hugo2
  • A.H. Scheel3
  • Merkelbach-Bruse3
  • E. Heinmöller1
  • R. Buettner3
  • B. Jasani4
  • J. Walbeck5
  • J.Rüschoff1,4,*,
  • P.Middel1

1Institute of Pathology Nordhessen, Kassel (Germany)

2Institute of Pathology, University Hospital Göttingen, Göttingen (Germany)

3Institute of Pathology, University Hospital Cologne, Cologne (Germany)

4Targos Molecular Pathology GmbH, Kassel (Germany)

5Regional Dysplasia Clinic Nordhessen, Kassel (Germany)

DOI: 10.31083/j.ejgo.2020.01.5093 Vol.41,Issue 1,February 2020 pp.80-84

Published: 15 February 2020

*Corresponding Author(s): J.Rüschoff E-mail:


The present study was conducted to examine the frequency of CIN/squamous intraepithelial lesions in patients after vaccination and respective HPV types observed at their referral to a regional center for screening of cervical dysplasia.


HPV; Vaccination; Cervical intraepithelial neoplasia.

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A.K. Fischer,K. Reuter-Jessen,H.-U. Schildhaus,T. Hugo,A.H. Scheel,Merkelbach-Bruse,E. Heinmöller,R. Buettner,B. Jasani,J. Walbeck,J.Rüschoff,P.Middel. Development of high-risk HPV associated cervical dysplasia despite HPV-vaccination: a regional dysplasia center cohort study. European Journal of Gynaecological Oncology. 2020. 41(1);80-84.


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