Malignant mixed mesonephric tumor arising in mesonephric carcinoma: a case report with complete remission after concurrent chemoradiation therapy

Purpose of Investigation: Malignant mixed mesonephric tumors very rarely arise in mesonephric carcinoma of the uterine cervix. These tumors tend to progress aggressively and belong to the histological group of mixed tumors with both epithelial and mesenchymal components. At diagnosis, most patients present with vaginal bleeding and a palpable mass in the cervix. Because this neoplasm is rare, there is no standard management for these patients, and they should be cared for on a case-by-case basis. Materials and Methods: The author treated a 74-year-old patient with a malignant mixed mesonephric tumor arising in the mesonephric carcinoma. The case report and a literature review are presented here. Results: Because the patient was elderly and had complicating medical problems, the authors could not perform surgical treatment and instead attempted concurrent chemoradiation (CCRT), which contrary to the authors’ expectations, resulted in complete remission. Conclusion: For patients with advanced-stage tumors and medically complicating issues, CCRT may represent an alternative therapeutic strategy.

Malignant mixed mesonephric tumor arising in mesonephric carcinoma; Concurrent chemoradiation; Complete remission; Cervix; Uterus.

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