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Endometrial stromal nodule: report of 8 cases and literature review

  • J. An1
  • G. Ruan1
  • X.Y. Xie2
  • Y.Q. Shi3
  • X.D. Mao1
  • B.H. Dong1
  • P.M. Sun1,*,

1Laboratory of Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

2Department of Gynecology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

3Department of Radiology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

DOI: 10.31083/j.ejgo.2020.03.5039 Vol.41,Issue 3,June 2020 pp.332-338

Submitted: 11 October 2018 Accepted: 25 February 2019

Published: 15 June 2020

*Corresponding Author(s): P.M. Sun E-mail: smabuchi@gyne.med.osaka-u.ac.jp

Abstract

Endometrial stromal nodule (ESN) is a rare and benign tumor of endometrial stromal origin that accounts for less than 10% of uterine mesenchymal neoplasms. It is difficult and yet essential to preoperatively differentiate endometrial stromal nodule from other types of mesenchymal malignancies, considering that the therapeutic options and clinical outcomes are totally different. To better guide clinical practice, the authors herein report eight cases diagnosed with endometrial stromal nodule and analyze the clinical and pathological characteristics, and also perform a literature review of endometrial stromal nodule. Authors of the present study conclude that conservative surgery with fertility-sparing is feasible for a suspected diagnosis of endometrial stromal nodule when ultrasonography suggests hypoechoic masses with cystic degeneration or liquefaction and magnetic resonance imaging showed a well circumscribed mass exhibiting isointensity on T1-weighted images, hyperintensity on T2-weighted images, and hyperintensity on diffusion-weighted images.

Keywords

Endometrial stromal nodule; Literature review; Magnetic resonance imaging; Fertility sparing; Treatment


Cite and Share

J. An, G. Ruan, X.Y. Xie, Y.Q. Shi,X.D. Mao, B.H. Dong, P.M. Sun. Endometrial stromal nodule: report of 8 cases and literature review. European Journal of Gynaecological Oncology. 2020. 41(3);332-338.

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