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Is there a difference between synchronous multiple primary cancer and metastasis cancer?

  • S. H. Chung1
  • J. H. Sang1,*,

1Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Bucheon 14584, Korea

DOI: 10.31083/j.ejgo.2020.03.5157 Vol.41,Issue 3,June 2020 pp.480-483

Submitted: 26 January 2018 Accepted: 11 April 2019

Published: 15 June 2020

*Corresponding Author(s): J. H. Sang E-mail: guardc@schmc.ac.kr

Abstract

The purpose of this study was to evaluate synchronous multiple primary neoplasms of gynecologic origin in terms of clinical features, diagnosis, treatment, and relapse. Seven patients treated from 2012 to 2017 were studied; five of whom had synchronous multiple primary neoplasms associated with endometrial cancer. Two patients recurred and additional chemotherapy was performed. Synchronous multiple primary neoplasms have a better prognosis than single metastatic tumors, but they should be followed up carefully, as they tend to recur in the latter half of treatment. The authors herein report these seven cases along with a brief review of the literature.

Keywords

Synchronous multiple primary neoplasms; Endometrial neoplasm; Ovarian neoplasm; Uterine cervical neoplasm

Cite and Share

S. H. Chung,J. H. Sang. Is there a difference between synchronous multiple primary cancer and metastasis cancer?. European Journal of Gynaecological Oncology. 2020. 41(3);480-483.

References

[1] Zaino R., Whitney C., Brady M.F., DeGeest K., Burger R.A., Buller R.E.: “Simultaneously detected endometrial and ovarian carcinomas—a prospective clinicopathologic study of 74 cases: a gynecologic oncology group study”. Gynecol. Oncol., 2001, 83, 355.

[2] Woodruff J.D., Solomon D., Sullivant H.: “Multifocal disease in the upper genital canal”. Obstet. Gynecol., 1985, 65, 695.

[3] Eisner R.F., Nieberg R.K., Berek J.S.: “Synchronous primary neoplasms of the female reproductive tract”. Gynecol. Oncol., 1989, 33, 335.

[4] Matlock D.L., Salem F.A., Charles E.H., Savage E.W.: “Synchronous multiple primary neoplasms of the upper female genital tract”. Gynecol. Oncol., 1982, 13, 271.

[5] Ayhan A., Yalcin O.T., Tuncer Z.S., Gurgan T., Kucukali T.: “Synchronous primary malignancies of the female genital tract”. Eur. J. Obstet. Gynecol. Reprod. Biol., 1992, 45, 63.

[6] Gemer O., Bergman M., Segal S.: “Ovarian metastasis in women with clinical stage I endometrial carcinoma”. Acta Obstet. Gynecol. Scand., 2004, 83, 208.

[7] Siegel R.L., Miller K.D., Jemal A.: “Cancer statistics, 2015”. CA Cancer J. Clin., 2015, 65, 5.

[8] Creasman W.T., Odicino F., Maisonneuve P., Quinn M.A., Beller U., Benedet J.L., et al.: “Carcinoma of the corpus uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer”. Int. J. Gynaecol. Obstet., 2006, 95, S105.

[9] Shenson D.L., Gallion H.H., Powell D.E., Pieretti M.: “Loss of heterozygosity and genomic instability in synchronous endometrioid tumors of the ovary and endometrium”. Cancer, 1995, 76, 650.

[10] Emmert-Buck M.R., Chuaqui R., Zhuang Z., Nogales F., Liotta L.A., Merino M.J.: “Molecular analysis of synchronous uterine and ovarian endometrioid tumors”. Int. J. Gynecol. Pathol., 1997, 16, 143.

[11] Fujita M., Enomoto T., Wada H., Inoue M., Okudaira Y., Shroyer K.R.: “Application of clonal analysis. Differential diagnosis for synchronous primary ovarian and endometrial cancers and metastatic cancer”. Am. J. Clin. Pathol., 1996, 105, 350.

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