Article Menu

Export Article

More by Authors Links

Article Data

  • Views 527
  • Dowloads 128

Case Reports

Open Access

Collision tumour of endometrial stromal sarcoma, uterine tumour resembling ovarian sex-cord tumour, and leiomyoma

  • Chiharu Mizoguchi1,*,
  • Harunobu Matsumoto1
  • Kaei Nasu1,2
  • Kentaro Kai1,3
  • Motoki Arakane4
  • Hisashi Narahara1

1Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan

2Division of Obstetrics and Gynecology, Support System for Community Medicine, Faculty of Medicine, Oita University, Oita, Japan

3Department of Obstetrics and Gynecology, Nakatsu Municipal Hospital, Oita, Japan

4Department of Diagnostic Pathology, Faculty of Medicine, Oita University, Oita, Japan

DOI: 10.31083/j.ejgo.2020.04.3936 Vol.41,Issue 4,August 2020 pp.634-637

Submitted: 30 July 2016 Accepted: 24 October 2019

Published: 15 August 2020

*Corresponding Author(s): Chiharu Mizoguchi E-mail: cmizoguchi@oita-u.ac.jp

PDF (1.55 MB)

Abstract

Purpose of investigation: Endometrial stromal (ES) tumours may show different types of differentiation including smooth muscle and sex-cord like elements. A common problem is the differential diagnosis of ES tumour variants from other tumours that have smooth muscle or sex cord-like elements. We report a case of collision tumour that was composed of a low-grade endometrial stromal sarcoma (ESS) with sex-cord like differentiation, a uterine tumour resembling ovarian sex-cord tumour (UTROSCT), and a leiomyoma. Result: The patient was a 63-year-old multiparous woman who was referred to us with the complaint of recurrent abnormal uterine bleeding. Magnetic resonance imaging demonstrated a 3.4-cm-dia. solid tumour in her uterine cavity. We performed an abdominal total hysterectomy and a bilateral salpingo-oophorectomy. On gross and microscopic examination, the tumour consisted of a CD10-positive low-grade ESS, a CD10-negative UTROSCT, and a leiomyoma. Conclusion: ESS should be distinguished from UTROSCT and leiomyoma because of its malignant potential.

Keywords

Endometrial stromal sarcoma; Leiomyoma; Sexcord differentiation; Uterine neoplasm; uterine tumour resembling ovarian

sexcord tumour

Cite and Share

Chiharu Mizoguchi,Harunobu Matsumoto,Kaei Nasu,Kentaro Kai,Motoki Arakane,Hisashi Narahara. Collision tumour of endometrial stromal sarcoma, uterine tumour resembling ovarian sex-cord tumour, and leiomyoma. European Journal of Gynaecological Oncology. 2020. 41(4);634-637.

URL:

https://www.ejgo.net/articles/10.31083/j.ejgo.2020.04.3936

References

[1] Xue W.C., Cheung A.N.: ”Endometrial stromal sarcoma of uterus”. Best Pract Res Clin Obstet Gynaecol. 2011, 25, 719.

[2] Munro M.G., Critchley H.O., Fraser I.S., Group F.M.D.W.: ”The FIGO classification of causes of abnormal uterine bleeding in the reproductive years”. Fertil Steril. 2011, 95, P2204.

[3] Oliva E., Clement P.B., Young R.H., Scully R.E.: ”Mixed endome­trial stromal and smooth muscle tumors of the uterus: a clinico­pathologic study of 15 cases”. Am J Surg Pathol. 1998, 22, 997.

[4] Clement P.B., Scully R.E.: ”Uterine tumors resembling ovarian sex­cord tumors. A clinicopathologic analysis of fourteen cases”. Am J Clin Pathol. 1976, 66, 512­25.

[5] Dionigi A., Oliva E., Clement P.B., Young R.H.: ”Endometrial stro­ mal nodules and endometrial stromal tumors with limited infiltra­tion: a clinicopathologic study of 50 cases”. Am J Surg Pathol. 2002, 26, 567.

[6] Feng W., Hua K., Gudlaugsson E., Yu Y., Zhou X., Baak J.P.: ”Prog­nostic indicators in WHO 2003 low­grade endometrial stromal sar­coma”. Histopathology. 2013, 62, 675.

[7] Chang K.L., Crabtree G.S., Lim­Tan S.K., Kempson R.L., Hen­drickson M.R.: ”Primary uterine endometrial stromal neoplasms. A clinicopathologic study of 117 cases”. Am J Surg Pathol. 1990, 14, 415.

[8] Kuman R.J., Carcangui M.L., Herrington C.S., Young R.H. Mes­-enchymal tumours. In: WHO Classification of Tumours of Female Reproductive Organs. 4th ed. Lyon, France: International Agency for Research on Cancer; 2014.

[9] Umeda S., Tateno M., Miyagi E., Sakurai K., Tanaka R., Tateishi Y., et al.: ”Uterine tumors resembling ovarian sex cord tumors (UTROSCT) with metastasis: clinicopathological study of two cases”. Int J Clin Exp Pathol. 2014, 7, 1051.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top