Article Menu

Export Article

More by Authors Links

Article Data

  • Views 532
  • Dowloads 133

Case Reports

Open Access

Perivascular epithelioid cell tumor arising in the left parametriu a case report

  • Soo-Young Lee1
  • Dae-Hyung Lee1,*,

1Department of Obstetrics & Gynecology, College of Medicine, Yeungnam University Medical Center, Daegu, Republic of Korea

DOI: 10.31083/j.ejgo.2020.04.5458 Vol.41,Issue 4,August 2020 pp.657-660

Submitted: 06 January 2020 Accepted: 17 June 2020

Published: 15 August 2020

*Corresponding Author(s): Dae-Hyung Lee E-mail: leebhy@ynu.ac.kr

PDF (993.64 kB)

Abstract

The perivascular epithelioid cell tumors (PEComas) mimic rare epithelial mesenchymal tumors with epithelioid features and perivascular clear cells that co-express the muscle and melanocytic markers. The PEComas include lymphangioleiomyomatosis, clear cell sugar tumor, angiomyolipoma, and myomelanocytic tumors. We report a case involving 37-year-old woman with a PEComa in the left parametrium. The patient was referred to our hospital with an adnexal tumor detected during medical examination. Therefore, she underwent laparoscopic mass excision surgery. Immunohistochemical staining of the tumor cells indicated positivity for Melan A, HMB45, and desmin. Finally, the tumor was diagnosed as a PEComa. The patient is undergoing regular follow-up, and no recurrence has been noted at 2 years after the surgery.

Keywords

Perivascular epithelioid cell tumors; Parametrium; Immunohistochemistry

Cite and Share

Soo-Young Lee,Dae-Hyung Lee. Perivascular epithelioid cell tumor arising in the left parametriu a case report. European Journal of Gynaecological Oncology. 2020. 41(4);657-660.

URL:

https://www.ejgo.net/articles/10.31083/j.ejgo.2020.04.5458

References

[1] Fletcher, C.D., Unni, K.K., Mertens, F. (eds.) World Health Organi­zation Classification of Tumours. Pathology and genetics of tumours of soft tissue and bone. 2002, Lyon: IARC Press.

[2] Pea M., Bonetti F., Zamboni G., Martignoni G., Fiore­Donati L., Doglioni C.: “Clear Cell Tumor and Angiomyolipoma”. Am. J. Surg. Pathol., 1991, 15, 199­200.

[3] Bonetti F., Pea M., Martignoni G., Zamboni G.: “PEC and Sugar”. Am. J. Surg. Pathol., 1992, 16, 307.

[4] Liu C., Chao W., Lin S., Lau H., Wu H., Wang P.: “Malig­nant perivascular epithelioid cell tumor in the female genital tract”. Medicine (Baltimore), 2019, 98, e14072.

[5] Bleeker J.S., Quevedo J.F., Folpe A.L.: “Malignant” Perivascu­lar Epithelioid Cell Neoplasm: Risk Stratification and Treatment Strategies”. Sarcoma, 2012, 2012, 1­12.

[6] Folpe A.L., Mentzel T., Lehr H., Fisher C., Balzer B.L., Weiss S.W.: “Perivascular Epithelioid Cell Neoplasms of Soft Tissue and Gyne­cologic Origin”. Am. J. Surg. Pathol., 2005, 29, 1558­1575.

[7] Scheppach W.: “PEComa of the colon resistant to sirolimus but re­sponsive to doxorubicinifosfamide”. World J. Gastroenterol., 2013, 19, 1657.

[8] Thway K., Fisher C.: “PEComa: morphology and genetics of a com­plex tumor family”. Ann. Diagn. Pathol., 2015, 19, 359­368.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top