Article Data

  • Views 793
  • Dowloads 132

Case Reports

Open Access

Unusual case of Krukenberg tumors diagnosed in early pregnancy

  • Adrius Gaurilcikas1,*,
  • Migle Gedgaudaite1
  • Saulius Paskauskas1
  • Tomas Birzietis2
  • Daiva Vaitkiene1

1Department of Obstetrics and Gynaecology, Lithuanian University of Health Sciences, Eiveniu 2, Kaunas LT50009, Lithuania

2Lithuanian University of Health Sciences, Clinic of Obstetrics and gynaecology. A. Mickeviciaus str. 9, Kaunas LT44307, Lithuania

DOI: 10.31083/j.ejgo.2020.05.5326 Vol.41,Issue 5,October 2020 pp.806-809

Submitted: 30 July 2019 Accepted: 30 October 2019

Published: 15 October 2020

*Corresponding Author(s): Adrius Gaurilcikas E-mail: adrius.gaurilcikas@lsmu.lt

Abstract

We present a case with Krukenberg tumors diagnosed in the first trimester of pregnancy. Ultrasound (US) led to early suspicion of the disease and serial scans allowed the natural course of metastatic gastric cancer to be followed. Successful treatment with palliative surgery and chemotherapy resulted in good maternal and foetal outcomes. International collaboration whereby the US findings were discussed with leading European experts enabled faster decision making during the clinical work-up of this rare case.


Keywords

Krukenberg tumor; Cancer in pregnancy; Gastric cancer; Metastatic ovarian tumors.


Cite and Share

Adrius Gaurilcikas,Migle Gedgaudaite,Saulius Paskauskas,Tomas Birzietis,Daiva Vaitkiene. Unusual case of Krukenberg tumors diagnosed in early pregnancy. European Journal of Gynaecological Oncology. 2020. 41(5);806-809.

References

[1] Woodruff J.D., Novak E.R.: “The Krukenberg tmour of the ovary: study of 48 cases from ovarian tumour registry”.Obstet. Gynecol., 1960; 15, 351.

[2] Yada-Hashimoto N., Yamamoto T., Kamiura S., Seino H., Ohira H., Sawai K. et al.: “Metastatic ovarian tumours: a review of 64 cases”. Gynecol. Oncol., 2003, 89, 314-317.

[3] Bloch M.H.: “Challenges of Fertility Sparing Ovarian Surgery Imposed by Krukenberg Tumors in Pregnancy”. Clin. Case Rep. Rev., 2015, 2.

[4] Shimizu H., Yamasaki M., Ohama K., Nozaki T., Tanaka Y.: “Characteristic Ultrasonographic Appearance of the Krukenberg Tumor”. J. Clin. Ultrasound, 1990, 18, 697-703.

[5] Testa A.C., Ferrandina G., Timmerman D., Savelli L., Ludovisi M., van Holsbeke C. et al.: “Imaging in gynecological disease (1): ultrasound features of metastases in the ovaries differ depending on the origin of the primary tumour”. Ultrasound Obstet. Gynecol., 2007, 29, 505-511.

[6] Testa A.C., Licameli A., Di Legge A., Mascilini F., Petruzziello L., Pelagalli M., et al.: “Color Doppler Sonographic Features of a Krukenberg Tumor in Pregnancy”. J. Ultrasound Med., 2009, 28, 695- 698.

[7] Chou M.M., Ho E.S.C., Lin N.F., Lee Y.H.: “Color Doppler sonographic appearance of a Krukenberg tumor in pregnancy”. Ultrasound Obstet. Gynecol., 1998, 11, 459-460.

[8] Kim S., Abd Halim S.R., Siddiqui N., Park W.E.: “Disseminated Cancer in Pregnancy: Krukenberg Tumour”. Case Reports in Obstetrics and Gynecology, 2014, 2014, 1-4.

[9] Co P.V., Gupta A., Attar B.M., Department of Medicine, Rush University Medical Center, Chicago, IL, USA., Demetria M.: “Gastric Cancer Presenting as a Krukenberg Tumor at 22 Weeks’ Gestation”. J. Gastric Cancer, 2014, 14, 275.

[10] Ozdegirmenci O., Kayikcioglu F., Haberal A., Ozfuttu A.: “Krukenberg tumor mimicking pregnancy luteoma”. Gynecol. Endocrinol., 2007, 23, 482-485.

[11] Timmerman D., Testa A.C., Bourne T., Ameye L., Jurkovic D., Van Holsbeke C., et al.: “Simple ultrasound-based rules for the diagnosis of ovarian cancer”. Ultrasound Obstet. Gynecol., 2008, 31, 681-690.

[12] Sakamoto K., Kanda T., Ohashi M., Kurabayashi T., Serikawa T., Matsunaga M. et al.: “Managment of patients with pregnany-associated gastric cancer in Japan: a mini-review”.Int. J. Clin. Oncol., 2009, 14, 392-396.

[13] Stec R., Lampka E., Kocian P. Gastro-intestinal cancer, In: editors, Textbook of Cancer in pregnancy. Nth Edition. ESGO eAcademy, ESGO, 2017: 3357.

[14] Kodama M., Moeini A., Machida H., Blake E.A., Grubbs B.H., Matsuo K.: “Fetomaternal outcomes of pregnancy complicated by Krukenberg tumor: a systematic review of literature”. Arch. Gynecol. Obstet., 2016, 294, 589-598.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top