Article Data

  • Views 730
  • Dowloads 156

Case Reports

Open Access

Breast Cancer Metastatic to Vulva - a Case Report

  • Katselashvili Lika1,*,
  • Jokhadze Natia1
  • Katcharava Margarita1
  • Vardiashvili Nino2

1Department of Hematology and Oncology, Research Institute of Clinical Medicine, Tbilisi, Georgia

2Oncology Department, Innova Medical Center, Tbilisi, Georgia

DOI: 10.31083/j.ejgo.2020.05.c5526 Vol.41,Issue 5,October 2020 pp.845-848

Submitted: 20 February 2020 Accepted: 27 April 2020

Published: 15 October 2020

*Corresponding Author(s): Katselashvili Lika E-mail: likakatselashvili@yahoo.com

Abstract

Vulvar cancer is a rare malignancy which accounts 3-5% of all gynecologic tumors. Metastases to the vulva are also rare but can have significant implications for both treatment and prognosis. Here we report a case of vulvar lesion which was the presenting sign of de novo stage IV breast cancer. We describe diagnostic and treatment approach which combined aggressive first-line treatment plus definitive therapy to her vulvar metastasis.


Keywords

Breast cancer; Metastases in the vulva; Invasive ductal carcinoma.


Cite and Share

Katselashvili Lika,Jokhadze Natia,Katcharava Margarita,Vardiashvili Nino. Breast Cancer Metastatic to Vulva - a Case Report. European Journal of Gynaecological Oncology. 2020. 41(5);845-848.

References

[1] Crum C., Herrington C.S., McCluggage W.G., Regauer S., Wilkin-son E.J.: “Tumors of the vulva”, in: WHO Classification of Tu-mours of Female Reproductive Organs (eds) Kurman R.J., Carcangiu M.L., Herrington C.S., Young R.H., , 4thedition. Lyon, IARC Press, 2014, pp 229-253.

[2] Mayo Clinic Staff (2017) Vulvar cancer. Available at: https://www.mayoclinic.org/diseases-conditions/vulvar-cancer/symptoms-causes/syc-20368051 (Accessed: February, 2020)

[3] Goncharenko V., Bubnov R., Polivka J., Zubor P., Biringer K., Bielik T., et al.: “Vaginal dryness: individualised patient profiles, risks and mitigating measures”. Epma Journal, 2019, 10, 73-79.

[4] Hunter D.J.S.: “Carcinoma of the vulva: A review of 361 patients”. Gynecol. Oncol., 1975, 3, 117-123.

[5] Brand A., Scurry J., Planner R., Leung S.: “Primary and Recurrent Colorectal Cancer Masquerading as Gynaecological Malignancy”. the Australian and New Zealand Journal of Obstetrics and Gynaecology, 1996, 36, 165-167.

[6] Neto A.G., Deavers M.T., Silva E.G., Malpica A.: “Metastatic Tumors of the Vulva”. the American Journal of Surgical Pathology, 2003, 27, 799-804.

[7] Oliva E., Carcangiu M., Carinelli S., Ip P., Loening T., Longacre T., et al.: “Tumours of the uterine corpus: mesenchymal tumours”, in: Kurman R.J., Carcangiu M.L., Herrington C.S. and Young R.H., WHO Classification of Tumours of Female Reproductive Organs, 4th edition. Lyon, IARC Press, 2014, pp 141-145.

[8] Porterhouse Medical Group Ltd (2019) World cancer day: What do the statistics say? Available at: https://www.iarc.fr/wp-content/uploads/2018/09/Globocan_02-e1536765200858.jpg (Accessed: September, 2019)

[9] Taxy J.B., Trujillo Y.P.: “Breast cancer metastatic to the uterus. Clinical manifestations of a rare event”. Archives of pathology & laboratory medicine. 1994; 118, 819-821.

[10] Dehner L.P.: “Metastatic and secondary tumors of the vulva”. Obstet. Gynecol., 1973, 4247-57.

[11] Borst M.J., Ingold J.A.: “Metastatic patterns of invasive lobular ver-sus invasive ductal carcinoma of the breast”. Surgery, 1993, 114, 637- 632.

[12] Cardoso F., Senkus E., Costa A., Papadopoulos E., Aapro M., André F., et al.: “4th ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4)”. Ann. Oncol., 2018, 29, 1634-1657.

[13] Simon K.E., Dutcher J.P., Runowicz C.D., Wiernik P.H.: “Adeno-carcinoma arising in vulvar breast tissue”. Cancer, 1988, 62, 2234-2238.

[14] Lee S., Nodit L.: “Phyllodes Tumor of Vulva: A Brief Diagnostic Review”. Archives of Pathology & Laboratory Medicine, 2014, 138, 1546-1550.

[15] Guglielmo P., Paderno M., Elisei F., Guerra L., Landoni C., Buda A., et al.: “18F-FDG PET/CT in a Case of Metastatic Breast Cancer to the Vulva”. Clin. Nucl. Med., 2019, 44, 572-573.

[16] Ishigaki T., Toriumi Y., Nosaka R., Kudou R., Imawari Y., Kamio M., et al.: “Primary ectopic breast cancer of the vulva, treated with local excision of the vulva and sentinel lymph node biopsy: a case report”. Surgical Case Reports, 2017, 3, 69.

[17] Covington E.E., William K., Brendle M.D.: “Breast Carcinoma with Vulvar Metastasis”. Obstetrics & Gynecology, 1964, 23(6): 910-911.

[18] Perrone G., Altomare V., Zagami M., Vulcano E., Muzii L., Battista C., et al.: “Breast-like vulvar lesion with concurrent breast cancer: a case report and critical literature review”. in vivo., 2009; 23(4): 629-634.

[19] Sheen-Chen S., Eng H., Huang C.: “Breast cancer metastatic to the vulva”. Gynecol. Oncol., 2004, 94, 858-860.

[20] Alligood-Percoco N.R., Kessler M.S., Willis G.: “Breast cancer metastasis to the vulva 20years remote from initial diagnosis: A case report and literature review”. Gynecologic Oncology Reports, 2015, 13, 33-35.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top