Article Data

  • Views 2635
  • Dowloads 173

Case Reports

Open Access

Breast Cancer Metastatic to Vulva - a Case Report

  • Katselashvili Lika1,*,
  • Jokhadze Natia1
  • Katcharava Margarita1
  • Vardiashvili Nino2

1Department of Hematology and Oncology, Research Institute of Clinical Medicine, Tbilisi, Georgia

2Oncology Department, Innova Medical Center, Tbilisi, Georgia

DOI: 10.31083/j.ejgo.2020.05.c5526 Vol.41,Issue 5,October 2020 pp.845-848

Submitted: 20 February 2020 Accepted: 27 April 2020

Published: 15 October 2020

*Corresponding Author(s): Katselashvili Lika E-mail: likakatselashvili@yahoo.com

Abstract

Vulvar cancer is a rare malignancy which accounts 3-5% of all gynecologic tumors. Metastases to the vulva are also rare but can have significant implications for both treatment and prognosis. Here we report a case of vulvar lesion which was the presenting sign of de novo stage IV breast cancer. We describe diagnostic and treatment approach which combined aggressive first-line treatment plus definitive therapy to her vulvar metastasis.


Keywords

Breast cancer; Metastases in the vulva; Invasive ductal carcinoma.


Cite and Share

Katselashvili Lika,Jokhadze Natia,Katcharava Margarita,Vardiashvili Nino. Breast Cancer Metastatic to Vulva - a Case Report. European Journal of Gynaecological Oncology. 2020. 41(5);845-848.

References

[1] Crum C., Herrington C.S., McCluggage W.G., Regauer S., Wilkin-son E.J.: “Tumors of the vulva”, in: WHO Classification of Tu-mours of Female Reproductive Organs (eds) Kurman R.J., Carcangiu M.L., Herrington C.S., Young R.H., , 4thedition. Lyon, IARC Press, 2014, pp 229-253.

[2] Mayo Clinic Staff (2017) Vulvar cancer. Available at: https://www.mayoclinic.org/diseases-conditions/vulvar-cancer/symptoms-causes/syc-20368051 (Accessed: February, 2020)

[3] Goncharenko V., Bubnov R., Polivka J., Zubor P., Biringer K., Bielik T., et al.: “Vaginal dryness: individualised patient profiles, risks and mitigating measures”. Epma Journal, 2019, 10, 73-79.

[4] Hunter D.J.S.: “Carcinoma of the vulva: A review of 361 patients”. Gynecol. Oncol., 1975, 3, 117-123.

[5] Brand A., Scurry J., Planner R., Leung S.: “Primary and Recurrent Colorectal Cancer Masquerading as Gynaecological Malignancy”. the Australian and New Zealand Journal of Obstetrics and Gynaecology, 1996, 36, 165-167.

[6] Neto A.G., Deavers M.T., Silva E.G., Malpica A.: “Metastatic Tumors of the Vulva”. the American Journal of Surgical Pathology, 2003, 27, 799-804.

[7] Oliva E., Carcangiu M., Carinelli S., Ip P., Loening T., Longacre T., et al.: “Tumours of the uterine corpus: mesenchymal tumours”, in: Kurman R.J., Carcangiu M.L., Herrington C.S. and Young R.H., WHO Classification of Tumours of Female Reproductive Organs, 4th edition. Lyon, IARC Press, 2014, pp 141-145.

[8] Porterhouse Medical Group Ltd (2019) World cancer day: What do the statistics say? Available at: https://www.iarc.fr/wp-content/uploads/2018/09/Globocan_02-e1536765200858.jpg (Accessed: September, 2019)

[9] Taxy J.B., Trujillo Y.P.: “Breast cancer metastatic to the uterus. Clinical manifestations of a rare event”. Archives of pathology & laboratory medicine. 1994; 118, 819-821.

[10] Dehner L.P.: “Metastatic and secondary tumors of the vulva”. Obstet. Gynecol., 1973, 4247-57.

[11] Borst M.J., Ingold J.A.: “Metastatic patterns of invasive lobular ver-sus invasive ductal carcinoma of the breast”. Surgery, 1993, 114, 637- 632.

[12] Cardoso F., Senkus E., Costa A., Papadopoulos E., Aapro M., André F., et al.: “4th ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4)”. Ann. Oncol., 2018, 29, 1634-1657.

[13] Simon K.E., Dutcher J.P., Runowicz C.D., Wiernik P.H.: “Adeno-carcinoma arising in vulvar breast tissue”. Cancer, 1988, 62, 2234-2238.

[14] Lee S., Nodit L.: “Phyllodes Tumor of Vulva: A Brief Diagnostic Review”. Archives of Pathology & Laboratory Medicine, 2014, 138, 1546-1550.

[15] Guglielmo P., Paderno M., Elisei F., Guerra L., Landoni C., Buda A., et al.: “18F-FDG PET/CT in a Case of Metastatic Breast Cancer to the Vulva”. Clin. Nucl. Med., 2019, 44, 572-573.

[16] Ishigaki T., Toriumi Y., Nosaka R., Kudou R., Imawari Y., Kamio M., et al.: “Primary ectopic breast cancer of the vulva, treated with local excision of the vulva and sentinel lymph node biopsy: a case report”. Surgical Case Reports, 2017, 3, 69.

[17] Covington E.E., William K., Brendle M.D.: “Breast Carcinoma with Vulvar Metastasis”. Obstetrics & Gynecology, 1964, 23(6): 910-911.

[18] Perrone G., Altomare V., Zagami M., Vulcano E., Muzii L., Battista C., et al.: “Breast-like vulvar lesion with concurrent breast cancer: a case report and critical literature review”. in vivo., 2009; 23(4): 629-634.

[19] Sheen-Chen S., Eng H., Huang C.: “Breast cancer metastatic to the vulva”. Gynecol. Oncol., 2004, 94, 858-860.

[20] Alligood-Percoco N.R., Kessler M.S., Willis G.: “Breast cancer metastasis to the vulva 20years remote from initial diagnosis: A case report and literature review”. Gynecologic Oncology Reports, 2015, 13, 33-35.


Submission Turnaround Time

Top