Malignant struma ovarii: a case report and literature review

Background: Struma ovarii accounts for 0.2–1.3% of all ovarian tumors and 2–4% of all teratomas. There is no guideline or international consensus for malignant struma ovarii treatment so far. Case presentation: We report a case of a 42-year-old woman who was diagnosed with malignant struma ovarii 18 years prior and remains alive. The patient presented with uncommon features of primary malignant struma ovarii, locoregional recurrence and metastases and received radical treatments including cytoreductive surgery (CRS), hyperthermic intraperitoneal chemotherapy (HIPEC), and transcatheter arterial chemoembolization (TACE). Conclusions: We report a typical case of malignant struma ovarii successfully treated by radical comprehensive treatment, with CRS + HIPEC as the core procedure. At present, the patient remains in good condition, surviving for 18 years since the tumor was found. This case provides evidence that CRS + HIPEC may be a promising strategy to improve outcomes for struma ovarii patients.

Strumaovarii; Livermetastases; Totalthyroidectomy; 131 I treatment; Cytoreduc- tive surgery; Hyperthermic intraperitoneal chemotherapy

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